Unraveling the mysteries of transcription

Tom Ellenberger

Research output: Contribution to journalShort survey

1 Scopus citations

Abstract

The crystal structure of bacteriophage T7 RNA polymerase complexed to a DNA promoter is the first high resolution structure of an open promoter complex. The orientation of the bound template and the structure of the polymerase active site suggest a model for transcript initiation.

Original languageEnglish
Pages (from-to)497-499
Number of pages3
JournalNature Structural Biology
Volume6
Issue number6
DOIs
StatePublished - Jun 9 1999

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