TY - JOUR
T1 - Unintended consequences of changes to lung allocation policy
AU - Puri, Varun
AU - Hachem, Ramsey R.
AU - Frye, Christian Corbin
AU - Harrison, Margaret Shea
AU - Semenkovich, Tara R.
AU - Lynch, John P.
AU - Ridolfi, Gene
AU - Rowe, Casey
AU - Meyers, Bryan F.
AU - Patterson, George Alexander
AU - Kozower, Benjamin D.
AU - Pasque, Michael K.
AU - Nava, Ruben G.
AU - Marklin, Gary F.
AU - Brockmeier, Diane
AU - Sweet, Stuart C.
AU - Chapman, William C.
AU - Kreisel, Daniel
N1 - Funding Information:
Varun Puri is supported by NIH K07 CA178120 and Mid-America Transplant Foundation 022017 research grants. Tara Semenkovich is supported by a Barnes Jewish Hospital Foundation grant. Daniel Kreisel is supported by the National Institutes of Health grants 1P01AI116501, R01 HL094601, Veterans Administration Merit Review grant 1I01BX002730, and The Foundation for Barnes-Jewish Hospital. Daniel Kreisel serves on the Scientific Advisory Board of Compass Therapeutics and receives research support from Compass Therapeutics.
Funding Information:
Barnes Jewish Hospital Foundation, Grant/ Award Number: Research Fellowship; Mid America Transplant Foundation, Grant/Award Number: 022017; National Institutes of Health, Grant/Award Number: 1P01AI116501, R01 HL094601 and NIH K07 CA178120; Center for Integrated Healthcare, U.S. Department of Veterans Affairs, Grant/Award Number: 1I01BX002730
Funding Information:
Varun Puri is supported by NIH K07 CA178120 and Mid‐America Transplant Foundation 022017 research grants. Tara Semenkovich is supported by a Barnes Jewish Hospital Foundation grant. Daniel Kreisel is supported by the National Institutes of Health grants 1P01AI116501, R01 HL094601, Veterans Administration Merit Review grant 1I01BX002730, and The Foundation for Barnes‐ Jewish Hospital. Daniel Kreisel serves on the Scientific Advisory Board of Compass Therapeutics and receives research support from Compass Therapeutics.
Publisher Copyright:
© 2019 The American Society of Transplantation and the American Society of Transplant Surgeons
PY - 2019/8
Y1 - 2019/8
N2 - Organ allocation for transplantation aims to balance the principles of justice and medical utility to optimally utilize a scarce resource. To address practical considerations, the United States is divided into 58 donor service areas (DSA), each constituting the first unit of allocation. In November 2017, in response to a lawsuit in New York, an emergency action change to lung allocation policy replaced the DSA level of allocation for donor lungs with a 250 nautical mile circle around the donor hospital. Similar policy changes are being implemented for other organs including heart and liver. Findings from a recent US Department of Health and Human Services report, supplemented with data from our institution, suggest that the emergency policy has not resulted in a change in the type of patients undergoing lung transplantation (LT) or early postoperative outcomes. However, there has been a significant decline in local LT, where donor and recipient are in the same DSA. With procurement teams having to travel greater distances, organ ischemic time has increased and median organ cost has more than doubled. We propose potential solutions for consideration at this critical juncture in the field of transplantation. Policymakers should choose equitable and sustainable access for this lifesaving discipline.
AB - Organ allocation for transplantation aims to balance the principles of justice and medical utility to optimally utilize a scarce resource. To address practical considerations, the United States is divided into 58 donor service areas (DSA), each constituting the first unit of allocation. In November 2017, in response to a lawsuit in New York, an emergency action change to lung allocation policy replaced the DSA level of allocation for donor lungs with a 250 nautical mile circle around the donor hospital. Similar policy changes are being implemented for other organs including heart and liver. Findings from a recent US Department of Health and Human Services report, supplemented with data from our institution, suggest that the emergency policy has not resulted in a change in the type of patients undergoing lung transplantation (LT) or early postoperative outcomes. However, there has been a significant decline in local LT, where donor and recipient are in the same DSA. With procurement teams having to travel greater distances, organ ischemic time has increased and median organ cost has more than doubled. We propose potential solutions for consideration at this critical juncture in the field of transplantation. Policymakers should choose equitable and sustainable access for this lifesaving discipline.
KW - clinical research/practice
KW - donors and donation
KW - editorial/personal viewpoint
KW - lung transplantation/pulmonology
KW - organ allocation
KW - organ procurement and allocation
UR - http://www.scopus.com/inward/record.url?scp=85069701036&partnerID=8YFLogxK
U2 - 10.1111/ajt.15307
DO - 10.1111/ajt.15307
M3 - Article
C2 - 30758137
AN - SCOPUS:85069701036
SN - 1600-6135
VL - 19
SP - 2164
EP - 2167
JO - American Journal of Transplantation
JF - American Journal of Transplantation
IS - 8
ER -