TY - JOUR
T1 - Undetectable plasma HIV RNA load predicts success after hepatitis B vaccination in HIV-infected persons
AU - Overton, Edgar Turner
AU - Sungkanuparph, Somnuek
AU - Powderly, William G.
AU - Seyfried, Warren
AU - Groger, Richard K.
AU - Aberg, Judith A.
N1 - Funding Information:
Financial support. Adult AIDS Clinical Trials Group, funded by the National Institute of Allergy and Infectious Diseases (AI-38858, AI-25903, and AI-27665). Potential conflicts of interest. All authors: no conflicts.
PY - 2005/10/1
Y1 - 2005/10/1
N2 - Human immunodeficiency virus (HIV)-infected patients respond poorly to hepatitis B vaccination. Records of 194 HIV-infected patients were reviewed for factors associated with successful hepatitis B vaccination. Thirty-four patients (17.5%) developed a protective antibody response. In a logistic regression model, only a plasma HIV RNA level of <400 copies/mL at the time of vaccination was associated with a protective antibody response (P = .003).
AB - Human immunodeficiency virus (HIV)-infected patients respond poorly to hepatitis B vaccination. Records of 194 HIV-infected patients were reviewed for factors associated with successful hepatitis B vaccination. Thirty-four patients (17.5%) developed a protective antibody response. In a logistic regression model, only a plasma HIV RNA level of <400 copies/mL at the time of vaccination was associated with a protective antibody response (P = .003).
UR - http://www.scopus.com/inward/record.url?scp=25444498267&partnerID=8YFLogxK
U2 - 10.1086/433180
DO - 10.1086/433180
M3 - Article
C2 - 16142673
AN - SCOPUS:25444498267
SN - 1058-4838
VL - 41
SP - 1045
EP - 1048
JO - Clinical Infectious Diseases
JF - Clinical Infectious Diseases
IS - 7
ER -