Ultrasound facilitates minimally invasive parathyroidectomy in patients lacking definitive localization from preoperative sestamibi scan

Matthew L. Davis, Frank J. Quayle, William D. Middleton, Lori M. Acosta, Staci J. Hix-Hernandez, Samuel K. Snyder, Jeffrey F. Moley, L. Michael Brunt, Terry C. Lairmore

Research output: Contribution to journalArticle

19 Scopus citations

Abstract

Background: Sestamibi scanning is commonly used for preoperative localization in patients with hyperparathyroidism. However, 12% to 15% of these studies are equivocal or negative. Ultrasound may also be used to identify patients suitable for a minimally invasive parathyroidectomy. Methods: Data from patients treated for hyperparathyroidism between January 2000 and April 2006 were reviewed retrospectively. Sestamibi and ultrasound results were scored as definitive, suggestive, or negative. Patients with suggestive or negative sestamibi scans were included in the analysis. Results: A total of 261 patients underwent operation without a definitively localizing sestamibi scan. Preoperative neck ultrasound was performed in 80 of these patients. Overall, ultrasound was either conclusive or suggestive in 45 of 80 patients (56%) without a definitively localizing sestamibi scan and correctly correlated with the surgical findings in 38 of 45 (84%) of these patients. Conclusion: In patients with nonlocalizing sestamibi scans, neck ultrasound increases the number of patients suitable for minimally invasive parathyroidectomy.

Original languageEnglish
Pages (from-to)785-791
Number of pages7
JournalAmerican journal of surgery
Volume194
Issue number6
DOIs
StatePublished - Dec 1 2007

Keywords

  • Minimally invasive parathyroidectomy
  • Sestamibi scanning
  • Ultrasound

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