Two cases of fungal keratitis caused by Metarhizium anisopliae

Abigail L. Goodman; Shawn R. Lockhart; Colleen B. Lysen; Lars F. Westblade; Carey Ann D. Burnham; Eileen M. Burd

doi:10.1016/j.mmcr.2018.03.003

Two cases of fungal keratitis caused by Metarhizium anisopliae

Abigail L. Goodman, Shawn R. Lockhart, Colleen B. Lysen, Lars F. Westblade, Carey Ann D. Burnham, Eileen M. Burd

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Abstract

We present two cases of keratitis due to Metarhizium anisopliae in geographically separated areas of the United States. The isolates were microscopically similar but morphologically different and were identified by ribosomal DNA sequencing. Both isolates had low minimum inhibitory concentration (MIC) values to caspofungin and micafungin, but high MIC values to amphotericin B. The morphologic and antifungal susceptibility differences between the two isolates indicate possible polyphylogeny of the group.

Original language	English
Pages (from-to)	8-11
Number of pages	4
Journal	Medical Mycology Case Reports
Volume	21
DOIs	https://doi.org/10.1016/j.mmcr.2018.03.003
State	Published - Sep 2018

Keywords

Antifungal susceptibility
Fungal keratitis
Keratomycosis
Metarhizium

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10.1016/j.mmcr.2018.03.003

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title = "Two cases of fungal keratitis caused by Metarhizium anisopliae",

abstract = "We present two cases of keratitis due to Metarhizium anisopliae in geographically separated areas of the United States. The isolates were microscopically similar but morphologically different and were identified by ribosomal DNA sequencing. Both isolates had low minimum inhibitory concentration (MIC) values to caspofungin and micafungin, but high MIC values to amphotericin B. The morphologic and antifungal susceptibility differences between the two isolates indicate possible polyphylogeny of the group.",

keywords = "Antifungal susceptibility, Fungal keratitis, Keratomycosis, Metarhizium",

author = "Goodman, {Abigail L.} and Lockhart, {Shawn R.} and Lysen, {Colleen B.} and Westblade, {Lars F.} and Burnham, {Carey Ann D.} and Burd, {Eileen M.}",

note = "Publisher Copyright: {\textcopyright} 2018 The Authors",

year = "2018",

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volume = "21",

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T1 - Two cases of fungal keratitis caused by Metarhizium anisopliae

AU - Goodman, Abigail L.

AU - Lockhart, Shawn R.

AU - Lysen, Colleen B.

AU - Westblade, Lars F.

AU - Burnham, Carey Ann D.

AU - Burd, Eileen M.

PY - 2018/9

Y1 - 2018/9

N2 - We present two cases of keratitis due to Metarhizium anisopliae in geographically separated areas of the United States. The isolates were microscopically similar but morphologically different and were identified by ribosomal DNA sequencing. Both isolates had low minimum inhibitory concentration (MIC) values to caspofungin and micafungin, but high MIC values to amphotericin B. The morphologic and antifungal susceptibility differences between the two isolates indicate possible polyphylogeny of the group.

AB - We present two cases of keratitis due to Metarhizium anisopliae in geographically separated areas of the United States. The isolates were microscopically similar but morphologically different and were identified by ribosomal DNA sequencing. Both isolates had low minimum inhibitory concentration (MIC) values to caspofungin and micafungin, but high MIC values to amphotericin B. The morphologic and antifungal susceptibility differences between the two isolates indicate possible polyphylogeny of the group.

KW - Antifungal susceptibility

KW - Fungal keratitis

KW - Keratomycosis

KW - Metarhizium

UR - http://www.scopus.com/inward/record.url?scp=85043520409&partnerID=8YFLogxK

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M3 - Article

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AN - SCOPUS:85043520409

SN - 2211-7539

VL - 21

SP - 8

EP - 11

JO - Medical Mycology Case Reports

JF - Medical Mycology Case Reports

ER -

Two cases of fungal keratitis caused by Metarhizium anisopliae

Abstract

Keywords

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