Turnover of the brain specific protein, S-100

Theodore J. Cicero; Blake W. Moore

doi:10.1126/science.169.3952.1333

Turnover of the brain specific protein, S-100

Theodore J. Cicero, Blake W. Moore

Department of Psychiatry

Research output: Contribution to journal › Article › peer-review

23 Scopus citations

Abstract

Rats were killed after intraventricular administration of [ ³H]leucine, and the turnover rates of total soluble proteins and of the brain specific S-100 protein were determined. The half-life of S-100 was estimated to be 16 days. The S-100 protein, thus, has a turnover not unlike that of the average water-soluble protein of brain.

Original language	English
Pages (from-to)	1333-1334
Number of pages	2
Journal	Science
Volume	169
Issue number	3952
DOIs	https://doi.org/10.1126/science.169.3952.1333
State	Published - 1970

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10.1126/science.169.3952.1333

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title = "Turnover of the brain specific protein, S-100",

abstract = "Rats were killed after intraventricular administration of [ 3H]leucine, and the turnover rates of total soluble proteins and of the brain specific S-100 protein were determined. The half-life of S-100 was estimated to be 16 days. The S-100 protein, thus, has a turnover not unlike that of the average water-soluble protein of brain.",

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AU - Cicero, Theodore J.

AU - Moore, Blake W.

PY - 1970

Y1 - 1970

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AB - Rats were killed after intraventricular administration of [ 3H]leucine, and the turnover rates of total soluble proteins and of the brain specific S-100 protein were determined. The half-life of S-100 was estimated to be 16 days. The S-100 protein, thus, has a turnover not unlike that of the average water-soluble protein of brain.

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U2 - 10.1126/science.169.3952.1333

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M3 - Article

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SN - 0036-8075

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EP - 1334

JO - Science

JF - Science

IS - 3952

ER -

Turnover of the brain specific protein, S-100

Abstract

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