Tumor necrosis factor-induced signal transduction and left ventricular remodeling

Research output: Contribution to journalArticle

44 Scopus citations

Abstract

Recent studies have identified the importance of biologically active molecules such as neurohormones in disease progression in heart failure. More recently, it has become apparent that in addition to neurohormones another portfolio of biologically active molecules termed cytokines are also expressed in the setting of heart failure. This article will review the role of tumor necrosis factor-induced signal transduction and the process of left ventricular remodeling.

Original languageEnglish
Pages (from-to)S379-S386
JournalJournal of cardiac failure
Volume8
Issue number6 SUPPL.
DOIs
StatePublished - Dec 2002
Externally publishedYes

Keywords

  • Hypertrophy
  • Remodeling
  • Signal transduction
  • Tumor necrosis factor

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