@article{8e5578f31ba44e20ab232ff270d63e8c,
title = "Tumor-Derived Retinoic Acid Regulates Intratumoral Monocyte Differentiation to Promote Immune Suppression",
abstract = "Tumor cells evade immune responses by producing high levels of retinoic acid, which directs intratumoral monocytes to differentiate into immunosuppressive macrophages rather than immunostimulatory dendritic cells.",
keywords = "dendritic cell, immune checkpoint blockade, immune evasion, macrophage, monocyte, retinoic acid, tumor microenvironment",
author = "Samir Devalaraja and To, {Tsun Ki Jerrick} and Folkert, {Ian W.} and Ramakrishnan Natesan and Alam, {Md Zahidul} and Minghong Li and Yuma Tada and Konstantin Budagyan and Dang, {Mai T.} and Li Zhai and Lobel, {Graham P.} and Ciotti, {Gabrielle E.} and Eisinger-Mathason, {T. S.Karin} and Asangani, {Irfan A.} and Kristy Weber and Simon, {M. Celeste} and Malay Haldar",
note = "Publisher Copyright: {\textcopyright} 2020 Elsevier Inc.",
year = "2020",
month = mar,
day = "19",
doi = "10.1016/j.cell.2020.02.042",
language = "English",
volume = "180",
pages = "1098--1114.e16",
journal = "Cell",
issn = "0092-8674",
number = "6",
}