Tumor-derived ILT4 induces T cell senescence and suppresses tumor immunity

Keyphrases

• Tumor 100%
• Tumor Immunity 100%
• T Cell Senescence 100%
• Immunoglobulin-like Transcript 4 100%
• Tumor Cells 33%
• Tumor Immunotherapy 25%
• Checkpoint Molecules 25%
• PirB 25%
• Breast Cancer 16%
• Quantitative PCR 16%
• Mouse Tumor Model 16%
• Effector T Cells 16%
• Immunohistochemistry 8%
• Clinical Outcomes 8%
• Success Rate 8%
• Cancer Tumor 8%
• Tumor Growth 8%
• Immune Suppression 8%
• Cancer Types 8%
• Loss Function 8%
• Signaling Molecules 8%
• Malignant Cells 8%
• Flow Cytometry 8%
• Cell Tumor 8%
• Orthologs 8%
• Multiplex Assay 8%
• Effective Strategies 8%
• ERK2 8%
• Tumor Microenvironment 8%
• Novel Mechanism 8%
• Tumor Progression 8%
• Nave 8%
• Negatively Associated 8%
• Western Blot 8%
• T-cell Mediated 8%
• Gain-of-function 8%
• Human Tumor Cells 8%
• Melanoma 8%
• Patient Samples 8%
• Tumor Metabolism 8%
• Tumor Patients 8%
• Cancer Biology 8%
• Fatty Acid Synthesis 8%
• Cell Samples 8%
• Lipid Droplets 8%
• Lipid Accumulation 8%
• Innate Cells 8%
• Multiple Markers 8%
• Metabolic Enzymes 8%
• Senescence 8%
• Background Current 8%
• Metabolic Signaling 8%
• Tumor-specific T Cells 8%
• Oil Red O Staining 8%
• Cell Senescence 8%
• Human Tumor Tissue 8%
• Checkpoint Blockade Therapy 8%
• Immunosuppressive Molecules 8%
• Melanoma Mouse Model 8%

Medicine and Dentistry

• Neoplasm 100%
• Immunoglobulin 100%
• T Cell 100%
• Tumor Immunity 100%
• Cellular Senescence 100%
• Tumor Cell 50%
• Cancer Immunotherapy 25%
• Malignant Neoplasm 16%
• Breast Cancer 16%
• Tumor Progression 16%
• Real Time Polymerase Chain Reaction 16%
• Melanoma 16%
• Immunohistochemistry 8%
• In Vitro 8%
• Immunosuppressive Treatment 8%
• Immunotherapy 8%
• Signaling Molecule 8%
• Flow Cytometry 8%
• Immunosuppressive Drug 8%
• Tumor Model 8%
• Specific Tumor 8%
• Mitogen Activated Protein Kinase 3 8%
• Lipid Storage 8%
• Mitogen-Activated Protein Kinase 8%
• Tumor Microenvironment 8%
• Orthology 8%
• Cancer Pathobiology 8%
• Tumor Metabolism 8%
• Digestant 8%
• Fat Droplet 8%
• Fatty Acid Synthesis 8%
• Western Blotting 8%

Immunology and Microbiology

• T Cell 100%
• Intravenous Immunoglobulin 100%
• Tumor Immunity 100%
• Tumor Cell 50%
• Cancer Immunotherapy 25%
• Real Time Polymerase Chain Reaction 16%
• Mouse Model 8%
• Myeloid 8%
• Immunosuppressive Drug 8%
• Immunotherapy 8%
• Western Blot 8%
• Orthology 8%
• Immunity 8%
• Fatty Acid Synthesis 8%
• Lipid Storage 8%