TY - JOUR
T1 - Triple analyzer mass spectrometry for high resolution MS/MS studies
AU - Gross, Michael L.
AU - Chess, Edward K.
AU - Lyon, Philip A.
AU - Crow, Frank W.
AU - Evans, Syd
AU - Tudge, Harold
N1 - Funding Information:
We thank F.W. McLafferty for helpful discussions regarding collision cell transmission characteristics and 33-L. Rempel for assistance with the measurements of cell transmission_ This work was supported by the Midwest Center for Mass Spectrometry, a National Science Foundation Regional Instrumentation Facility (Grant No. CHE 78-18572) and by the National Science Foundation (Grant No. CHE 8008008 to M.L.G.).
PY - 1982/5
Y1 - 1982/5
N2 - A high resolution MS/MS instrument comprising electrostatic analyzer, magnetic sector, electrostatic analyzer (EBE) is described. Analytical applications of this instrument require high resolution mass selection, high dynamic range and good transmission for collision-induced decomposition (CID) fragments. Suitable experiments are reported as an evaluation of these requirements. It is found that CID spectra can be obtained for ion components separated at a mass resolution of 100 000. At lower resolving powers, a dynamic range of 100 000 for mixture constituents is demonstrated. Finally, a transmission of 4% for ion fragments produced in CID from methane is established.
AB - A high resolution MS/MS instrument comprising electrostatic analyzer, magnetic sector, electrostatic analyzer (EBE) is described. Analytical applications of this instrument require high resolution mass selection, high dynamic range and good transmission for collision-induced decomposition (CID) fragments. Suitable experiments are reported as an evaluation of these requirements. It is found that CID spectra can be obtained for ion components separated at a mass resolution of 100 000. At lower resolving powers, a dynamic range of 100 000 for mixture constituents is demonstrated. Finally, a transmission of 4% for ion fragments produced in CID from methane is established.
UR - http://www.scopus.com/inward/record.url?scp=0000715980&partnerID=8YFLogxK
U2 - 10.1016/0020-7381(82)80069-7
DO - 10.1016/0020-7381(82)80069-7
M3 - Article
AN - SCOPUS:0000715980
SN - 0020-7381
VL - 42
SP - 243
EP - 254
JO - International Journal of Mass Spectrometry and Ion Physics
JF - International Journal of Mass Spectrometry and Ion Physics
IS - 4
ER -