Triglyceride lipase

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review


Triglycerides comprise 95% of the fats in the Western diet. For efficient uptake by intestinal enterocytes, triglycerides must be hydrolyzed into free fatty acids and monoacylglycerides. Pancreatic triglyceride lipase is the predominant enzyme required for the efficient digestion of triglycerides. Pancreatic triglyceride lipase is synthesized and secreted by pancreatic acinar cells and requires another protein, colipase, for full activity in the presence of physiological concentrations of bile salts, phospholipids, dietary proteins, and cholesterol esters.

Original languageEnglish
Title of host publicationxPharm
Subtitle of host publicationThe Comprehensive Pharmacology Reference
PublisherElsevier Inc.
Number of pages10
ISBN (Print)9780080552323
StatePublished - Jan 1 2007


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