Triglyceride lipase

Mark E. Lowe

doi:10.1016/B978-008055232-3.60537-9

Triglyceride lipase

Mark E. Lowe

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

1 Scopus citations

Abstract

Triglycerides comprise 95% of the fats in the Western diet. For efficient uptake by intestinal enterocytes, triglycerides must be hydrolyzed into free fatty acids and monoacylglycerides. Pancreatic triglyceride lipase is the predominant enzyme required for the efficient digestion of triglycerides. Pancreatic triglyceride lipase is synthesized and secreted by pancreatic acinar cells and requires another protein, colipase, for full activity in the presence of physiological concentrations of bile salts, phospholipids, dietary proteins, and cholesterol esters.

Original language	English
Title of host publication	xPharm
Subtitle of host publication	The Comprehensive Pharmacology Reference
Publisher	Elsevier Inc.
Pages	1-10
Number of pages	10
ISBN (Print)	9780080552323
DOIs	https://doi.org/10.1016/B978-008055232-3.60537-9
State	Published - Jan 1 2007

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10.1016/B978-008055232-3.60537-9

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AB - Triglycerides comprise 95% of the fats in the Western diet. For efficient uptake by intestinal enterocytes, triglycerides must be hydrolyzed into free fatty acids and monoacylglycerides. Pancreatic triglyceride lipase is the predominant enzyme required for the efficient digestion of triglycerides. Pancreatic triglyceride lipase is synthesized and secreted by pancreatic acinar cells and requires another protein, colipase, for full activity in the presence of physiological concentrations of bile salts, phospholipids, dietary proteins, and cholesterol esters.

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Triglyceride lipase

Abstract

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