@article{17fc51faa82e4916bf63cecf4eb3c4d1,
title = "TREM2 Modulation Remodels the Tumor Myeloid Landscape Enhancing Anti-PD-1 Immunotherapy",
abstract = "TREM2 is a pro-tumorigenic marker of tumor-infiltrating macrophages in mouse models and human tumors that can be targeted to curb tumor growth and improve the efficacy of checkpoint blockade therapy while remodeling the landscape of tumor-infiltrating macrophages.",
keywords = "TREM2, breast cancer, checkpoint blockade, colorectal cancer, human, macrophages, sarcoma, tumor",
author = "Martina Molgora and Ekaterina Esaulova and William Vermi and Jinchao Hou and Yun Chen and Jingqin Luo and Simone Brioschi and Mattia Bugatti and Omodei, {Andrea Salvatore} and Biancamaria Ricci and Catrina Fronick and Panda, {Santosh K.} and Yoshiko Takeuchi and Gubin, {Matthew M.} and Roberta Faccio and Marina Cella and Susan Gilfillan and Unanue, {Emil R.} and Artyomov, {Maxim N.} and Schreiber, {Robert D.} and Marco Colonna",
note = "Publisher Copyright: {\textcopyright} 2020 Elsevier Inc.",
year = "2020",
month = aug,
day = "20",
doi = "10.1016/j.cell.2020.07.013",
language = "English",
volume = "182",
pages = "886--900.e17",
journal = "Cell",
issn = "0092-8674",
number = "4",
}