TREM2-dependent effects on microglia in Alzheimer's Disease

Keyphrases

• Microglia 100%
• Alzheimer's Disease 100%
• Triggering Receptor Expressed on Myeloid Cells 2 (TREM2) 100%
• Alzheimer's Disease Pathology 30%
• Central Nervous System 20%
• Plaque 20%
• Metabolism 20%
• Microglial Metabolism 20%
• Risk Factors 10%
• Odds Ratio 10%
• Disease Progression 10%
• Microglial Response 10%
• Microglial Activation 10%
• Genome-wide Association Study 10%
• Amyloid Plaques 10%
• Alzheimer's Disease Model 10%
• Late-onset Alzheimer's Disease 10%
• Adaptor Protein 10%
• Innate Immune Cells 10%
• Transmembrane Domain 10%
• Neuronal Loss 10%
• Neurofibrillary Tangles 10%
• Alzheimer's Disease Brain 10%
• Cognitive Deficits 10%
• Amyloid Formation 10%
• Protein Aggregates 10%
• Glial Response 10%
• Reactive Astrocytes 10%
• R47H 10%
• Cell Metabolism 10%
• DAP12 10%
• Immunoreceptor Tyrosine-based Activation Motif 10%
• Mammalian Target of Rapamycin Pathway 10%
• Reactive Microglia 10%
• Immunoreceptor 10%
• Polyanionic Materials 10%
• Surrounding Environment 10%
• Abnormal Proteins 10%
• Late-onset Dementia 10%

Neuroscience

• Alzheimer's Disease 100%
• Microglia 100%
• Triggering Receptor Expressed on Myeloid Cells 2 100%
• Metabolic Pathway 55%
• Central Nervous System 22%
• Amyloid Protein 22%
• Cognitive Disorders 11%
• Astrocyte 11%
• Adaptor Protein 11%
• Mammalian Target of Rapamycin 11%
• Genome-Wide Association Study 11%
• Protein Aggregate 11%
• Immunoreceptor Tyrosine Based Activation Motif 11%

Medicine and Dentistry

• Triggering Receptor Expressed on Myeloid Cells 2 100%
• Alzheimer's Disease 100%
• Microglia 100%
• Central Nervous System 22%
• Amyloid Protein 22%
• Immunocompetent Cell 11%
• Disease Exacerbation 11%
• Amyloid Plaque 11%
• Genome Wide Association Study 11%
• Cognitive Defect 11%
• Mechanistic Target of Rapamycin 11%
• Astrocyte 11%
• Immunoreceptor Tyrosine Based Activation Motif 11%
• Protein Aggregate 11%
• Adaptor Protein 11%
• Neurofibrillary Tangle 11%
• Odds Ratio 11%