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TREM2-dependent effects on microglia in Alzheimer's Disease
Yingyue Zhou
, Tyler K. Ulland
,
Marco Colonna
Roy and Diana Vagelos Division of Biology & Biomedical Sciences (DBBS)
Institute of Clinical and Translational Sciences (ICTS)
Siteman Cancer Center
Division of Immunobiology
Bursky Center for Human Immunology and Immunotherapy
Center for Brain Immunology & Glia (BIG)
Rheumatic Diseases Research Resource-Based Center
DBBS - Immunology
DBBS - Molecular Microbiology and Microbial Pathogenesis
Hope Center for Neurological Disorders
Research output
:
Contribution to journal
›
Short survey
›
peer-review
78
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Scopus citations
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Keyphrases
Microglia
100%
Alzheimer's Disease
100%
Triggering Receptor Expressed on Myeloid Cells 2 (TREM2)
100%
Alzheime's Disease
100%
Central Nervous System
20%
Plaque
20%
Alzheimer's Disease Pathology
20%
Microglial Metabolism
20%
Risk Factors
10%
Odds Ratio
10%
Disease Progression
10%
Microglial Response
10%
Microglial Activation
10%
Genome-wide Association Study
10%
Amyloid Plaques
10%
Late-onset Alzheimer's Disease
10%
Metabolism
10%
Adaptor Protein
10%
Innate Immune Cells
10%
Transmembrane Domain
10%
Neuronal Loss
10%
Neurofibrillary Tangles
10%
Alzheimer's Disease Brain
10%
Cognitive Deficits
10%
Amyloid Formation
10%
Protein Aggregates
10%
Glial Response
10%
Reactive Astrocytes
10%
Cell Metabolism
10%
DAP12
10%
Immunoreceptor Tyrosine-based Activation Motif
10%
Reactive Microglia
10%
Immunoreceptor
10%
Mammalian Target of Rapamycin Signaling Pathway
10%
Surrounding Environment
10%
Late-onset Dementia
10%
Alzheimer's Disease Mouse Model
10%
Alzheimer's Disease Pathogenesis
10%
Abnormal Protein
10%
R47H Variant
10%
Polyanionic
10%
Aberrant Metabolism
10%
Neuroscience
Alzheimer's Disease
100%
Microglia
100%
Triggering Receptor Expressed on Myeloid Cells 2
100%
Metabolic Pathway
55%
Plaque
33%
Central Nervous System
22%
Amyloid Protein
22%
Cognitive Disorders
11%
Astrocyte
11%
Adaptor Protein
11%
Mammalian Target of Rapamycin
11%
Genome-Wide Association Study
11%
Protein Aggregate
11%
Immunoreceptor Tyrosine Based Activation Motif
11%
Risk Factor
11%
Neurofibrillary Tangle
11%
Medicine and Dentistry
Triggering Receptor Expressed on Myeloid Cells 2
100%
Alzheimer's Disease
100%
Microglia
100%
Central Nervous System
22%
Amyloid Protein
22%
Immunocompetent Cell
11%
Disease Exacerbation
11%
Amyloid Plaque
11%
Genome Wide Association Study
11%
Cognitive Defect
11%
Mechanistic Target of Rapamycin
11%
Astrocyte
11%
Immunoreceptor Tyrosine Based Activation Motif
11%
Protein Aggregate
11%
Adaptor Protein
11%
Neurofibrillary Tangle
11%
Odds Ratio
11%
Pathogenesis
11%