Treatment-resistant depression in children and adolescents

B. Geller, R. D. Todd, J. Luby, K. N. Botteron

Research output: Contribution to journalArticlepeer-review

18 Scopus citations


Treatment resistance in depressed children and adolescents cannot yet be defined fully because of the paucity of controlled studies that demonstrate efficacy. Therefore, this article addresses several of the age-specific, developmental considerations that may impinge upon treatment response. Areas covered include familial-genetic, psychosocial, and neuroimaging studies in addition to a review of controlled studies to date.

Original languageEnglish
Pages (from-to)253-267
Number of pages15
JournalPsychiatric Clinics of North America
Issue number2
StatePublished - 1996


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