TY - JOUR
T1 - Treatment-resistant depression in children and adolescents
AU - Geller, B.
AU - Todd, R. D.
AU - Luby, J.
AU - Botteron, K. N.
N1 - Funding Information:
This work was supported by grants R01–MH40646, R01–MH40273, and R01–MH45486 to Dr. Geller and by grant P50–MH30381 from the National Institute of Mental Health.
PY - 1996
Y1 - 1996
N2 - Treatment resistance in depressed children and adolescents cannot yet be defined fully because of the paucity of controlled studies that demonstrate efficacy. Therefore, this article addresses several of the age-specific, developmental considerations that may impinge upon treatment response. Areas covered include familial-genetic, psychosocial, and neuroimaging studies in addition to a review of controlled studies to date.
AB - Treatment resistance in depressed children and adolescents cannot yet be defined fully because of the paucity of controlled studies that demonstrate efficacy. Therefore, this article addresses several of the age-specific, developmental considerations that may impinge upon treatment response. Areas covered include familial-genetic, psychosocial, and neuroimaging studies in addition to a review of controlled studies to date.
UR - http://www.scopus.com/inward/record.url?scp=0029946062&partnerID=8YFLogxK
U2 - 10.1016/S0193-953X(05)70287-2
DO - 10.1016/S0193-953X(05)70287-2
M3 - Article
C2 - 8827189
AN - SCOPUS:0029946062
SN - 0193-953X
VL - 19
SP - 253
EP - 267
JO - Psychiatric Clinics of North America
JF - Psychiatric Clinics of North America
IS - 2
ER -