Treatment recommendations in Primary Ciliary Dyskinesia

Deepika Polineni, Stephanie D. Davis, Sharon D. Dell

Research output: Contribution to journalReview articlepeer-review

22 Scopus citations


Primary Ciliary Dyskinesia (PCD) is a rare heterogenic disorder leading to significant respiratory morbidity. Health-care providers who treat PCD must familiarize themselves with recommended treatment strategies. However, most of the treatments recommended in PCD have been extrapolated from cystic fibrosis (CF) and non-CF bronchiectasis literature. Mainstays of therapy are reviewed in detail, and should include at a minimum: regular airway clearance, routine microbiological surveillance, antibiotic treatment for pulmonary exacerbation, and health vaccinations. This review summarizes both medical and surgical pulmonary treatment considerations, as well as recommendations for the integration of non-pulmonary subspecialty care in the management of PCD.

Original languageEnglish
Pages (from-to)39-45
Number of pages7
JournalPaediatric Respiratory Reviews
StatePublished - Mar 1 2016


  • Bronchiectasis
  • Mucociliary clearance
  • Primary ciliary dyskinesia
  • Treatments


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