TY - JOUR
T1 - Treatment of periprosthetic joint infection of the elbow
T2 - 15-year experience at a single institution
AU - Zmistowski, Benjamin
AU - Pourjafari, Alborz
AU - Padegimas, Eric M.
AU - Sheth, Mihir
AU - Cox, Ryan M.
AU - Ramsey, Matthew L.
AU - Horneff, John G.
AU - Namdari, Surena
N1 - Funding Information:
Surena Namdari receives research funding from DePuy, Zimmer, DJO Surgical, Tornier, Integra Life Sciences, and Arthrex; is a consultant for DJO Surgical, DePuy Synthes, and Miami Device Solutions; and receives royalties from DJO Surgical, Miami Device Solutions, and Elsevier.
Publisher Copyright:
© 2018 Journal of Shoulder and Elbow Surgery Board of Trustees
PY - 2018/9
Y1 - 2018/9
N2 - Background: Total elbow arthroplasty (TEA) can be complicated by periprosthetic joint infection (PJI) with potentially catastrophic failure. The purpose of this study was to describe the results of elbow PJI treatment at a tertiary-care referral center. Methods: An institutional TEA database was queried for infection and reoperation after TEA. Patients who underwent irrigation and débridement (I&D) with component retention were compared with those who underwent component explantation, antibiotic spacer placement, and reimplantation of a revision TEA. Results: A total of 26 patients (10 men; mean age, 64.3 years) were treated for PJI of TEA. There were 3 polymicrobial infections (11.5%) and 13 Staphylococcus aureus infections (50%) (4 methicillin resistant); 6 patients (23.1%) had negative culture results. Ten patients (38.5%) underwent I&D and component retention, with 5 of those patients (5 of 10, 50%) having recurrent infection at an average of 3.1 years (range, 0.25-7.8 years) after I&D. Of 16 patients who underwent antibiotic spacer placement, 12 (75%) underwent 2-stage reimplantation of a TEA. Among those with reimplantation, 4 of 12 (33.3%) required reoperation. In 3 of 12 (25.0%), reoperation was required for infection, whereas 1 of 12 (8.3%) required surgery for mechanical complications. Conclusion: Two-stage revision results in a decreased rate of recurrent PJI. Certain patients (those with poor health or well-fixed components) may be more suitable for I&D and component retention, with a demonstrated 50% success rate over a period of 3 years. Longer-term follow-up may result in higher reinfection rates in both groups.
AB - Background: Total elbow arthroplasty (TEA) can be complicated by periprosthetic joint infection (PJI) with potentially catastrophic failure. The purpose of this study was to describe the results of elbow PJI treatment at a tertiary-care referral center. Methods: An institutional TEA database was queried for infection and reoperation after TEA. Patients who underwent irrigation and débridement (I&D) with component retention were compared with those who underwent component explantation, antibiotic spacer placement, and reimplantation of a revision TEA. Results: A total of 26 patients (10 men; mean age, 64.3 years) were treated for PJI of TEA. There were 3 polymicrobial infections (11.5%) and 13 Staphylococcus aureus infections (50%) (4 methicillin resistant); 6 patients (23.1%) had negative culture results. Ten patients (38.5%) underwent I&D and component retention, with 5 of those patients (5 of 10, 50%) having recurrent infection at an average of 3.1 years (range, 0.25-7.8 years) after I&D. Of 16 patients who underwent antibiotic spacer placement, 12 (75%) underwent 2-stage reimplantation of a TEA. Among those with reimplantation, 4 of 12 (33.3%) required reoperation. In 3 of 12 (25.0%), reoperation was required for infection, whereas 1 of 12 (8.3%) required surgery for mechanical complications. Conclusion: Two-stage revision results in a decreased rate of recurrent PJI. Certain patients (those with poor health or well-fixed components) may be more suitable for I&D and component retention, with a demonstrated 50% success rate over a period of 3 years. Longer-term follow-up may result in higher reinfection rates in both groups.
KW - Elbow arthroplasty
KW - Level III
KW - Retrospective Cohort Design
KW - Treatment Study
KW - complications
KW - elbow periprosthetic joint infection
KW - infection
KW - reoperations
KW - total elbow
UR - http://www.scopus.com/inward/record.url?scp=85050199340&partnerID=8YFLogxK
U2 - 10.1016/j.jse.2018.05.035
DO - 10.1016/j.jse.2018.05.035
M3 - Article
AN - SCOPUS:85050199340
SN - 1058-2746
VL - 27
SP - 1636
EP - 1641
JO - Journal of Shoulder and Elbow Surgery
JF - Journal of Shoulder and Elbow Surgery
IS - 9
ER -