Treatment of multiple myeloma: ASCO and CCO joint clinical practice guideline

Joseph Mikhael; Nofisat Ismaila; Matthew C. Cheung; Caitlin Costello; Madhav V. Dhodapkar; Shaji Kumar; Martha Lacy; Brea Lipe; Richard F. Little; Anna Nikonova; James Omel; Namrata Peswani; Anca Prica; Noopur Raje; Rahul Seth; David H. Vesole; Irwin Walker; Alexander Whitley; Tanya M. Wildes; Sandy W. Wong; Tom Martin

doi:10.1200/JCO.18.02096

Treatment of multiple myeloma: ASCO and CCO joint clinical practice guideline

Joseph Mikhael, Nofisat Ismaila, Matthew C. Cheung, Caitlin Costello, Madhav V. Dhodapkar, Shaji Kumar, Martha Lacy, Brea Lipe, Richard F. Little, Anna Nikonova, James Omel, Namrata Peswani, Anca Prica, Noopur Raje, Rahul Seth, David H. Vesole, Irwin Walker, Alexander Whitley, Tanya M. Wildes, Sandy W. WongTom Martin

Research output: Contribution to journal › Review article › peer-review

204 Scopus citations

Abstract

PURPOSE To provide evidence-based recommendations on the treatment of multiple myeloma to practicing physicians and others. METHODS ASCO and Cancer Care Ontario convened an Expert Panel of medical oncology, surgery, radiation oncology, and advocacy experts to conduct a literature search, which included systematic reviews,meta-analyses, randomized controlled trials, and some phase II studies published from 2005 through 2018. Outcomes of interest included survival, progression-free survival, response rate, and quality of life. Expert Panel members used available evidence and informal consensus to develop evidence-based guideline recommendations. RESULTS The literature search identified 124 relevant studies to inform the evidence base for this guideline. RECOMMENDATIONS Evidence-based recommendations were developed for patients with multiple myeloma who are transplantation eligible and those who are ineligible and for patients with relapsed or refractory disease. Additional information is available at www.asco.org/hematologic-malignancies-guidelines.

Original language	English
Pages (from-to)	1228-1263
Number of pages	36
Journal	Journal of Clinical Oncology
Volume	37
Issue number	14
DOIs	https://doi.org/10.1200/JCO.18.02096
State	Published - 2019

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Mikhael, J., Ismaila, N., Cheung, M. C., Costello, C., Dhodapkar, M. V., Kumar, S., Lacy, M., Lipe, B., Little, R. F., Nikonova, A., Omel, J., Peswani, N., Prica, A., Raje, N., Seth, R., Vesole, D. H., Walker, I., Whitley, A., Wildes, T. M., ... Martin, T. (2019). Treatment of multiple myeloma: ASCO and CCO joint clinical practice guideline. Journal of Clinical Oncology, 37(14), 1228-1263. https://doi.org/10.1200/JCO.18.02096

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title = "Treatment of multiple myeloma: ASCO and CCO joint clinical practice guideline",

abstract = "PURPOSE To provide evidence-based recommendations on the treatment of multiple myeloma to practicing physicians and others. METHODS ASCO and Cancer Care Ontario convened an Expert Panel of medical oncology, surgery, radiation oncology, and advocacy experts to conduct a literature search, which included systematic reviews,meta-analyses, randomized controlled trials, and some phase II studies published from 2005 through 2018. Outcomes of interest included survival, progression-free survival, response rate, and quality of life. Expert Panel members used available evidence and informal consensus to develop evidence-based guideline recommendations. RESULTS The literature search identified 124 relevant studies to inform the evidence base for this guideline. RECOMMENDATIONS Evidence-based recommendations were developed for patients with multiple myeloma who are transplantation eligible and those who are ineligible and for patients with relapsed or refractory disease. Additional information is available at www.asco.org/hematologic-malignancies-guidelines.",

author = "Joseph Mikhael and Nofisat Ismaila and Cheung, {Matthew C.} and Caitlin Costello and Dhodapkar, {Madhav V.} and Shaji Kumar and Martha Lacy and Brea Lipe and Little, {Richard F.} and Anna Nikonova and James Omel and Namrata Peswani and Anca Prica and Noopur Raje and Rahul Seth and Vesole, {David H.} and Irwin Walker and Alexander Whitley and Wildes, {Tanya M.} and Wong, {Sandy W.} and Tom Martin",

year = "2019",

doi = "10.1200/JCO.18.02096",

language = "English",

volume = "37",

pages = "1228--1263",

journal = "Journal of Clinical Oncology",

issn = "0732-183X",

number = "14",

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Mikhael, J, Ismaila, N, Cheung, MC, Costello, C, Dhodapkar, MV, Kumar, S, Lacy, M, Lipe, B, Little, RF, Nikonova, A, Omel, J, Peswani, N, Prica, A, Raje, N, Seth, R, Vesole, DH, Walker, I, Whitley, A, Wildes, TM, Wong, SW & Martin, T 2019, 'Treatment of multiple myeloma: ASCO and CCO joint clinical practice guideline', Journal of Clinical Oncology, vol. 37, no. 14, pp. 1228-1263. https://doi.org/10.1200/JCO.18.02096

TY - JOUR

T1 - Treatment of multiple myeloma

T2 - ASCO and CCO joint clinical practice guideline

AU - Mikhael, Joseph

AU - Ismaila, Nofisat

AU - Cheung, Matthew C.

AU - Costello, Caitlin

AU - Dhodapkar, Madhav V.

AU - Kumar, Shaji

AU - Lacy, Martha

AU - Lipe, Brea

AU - Little, Richard F.

AU - Nikonova, Anna

AU - Omel, James

AU - Peswani, Namrata

AU - Prica, Anca

AU - Raje, Noopur

AU - Seth, Rahul

AU - Vesole, David H.

AU - Walker, Irwin

AU - Whitley, Alexander

AU - Wildes, Tanya M.

AU - Wong, Sandy W.

AU - Martin, Tom

PY - 2019

Y1 - 2019

N2 - PURPOSE To provide evidence-based recommendations on the treatment of multiple myeloma to practicing physicians and others. METHODS ASCO and Cancer Care Ontario convened an Expert Panel of medical oncology, surgery, radiation oncology, and advocacy experts to conduct a literature search, which included systematic reviews,meta-analyses, randomized controlled trials, and some phase II studies published from 2005 through 2018. Outcomes of interest included survival, progression-free survival, response rate, and quality of life. Expert Panel members used available evidence and informal consensus to develop evidence-based guideline recommendations. RESULTS The literature search identified 124 relevant studies to inform the evidence base for this guideline. RECOMMENDATIONS Evidence-based recommendations were developed for patients with multiple myeloma who are transplantation eligible and those who are ineligible and for patients with relapsed or refractory disease. Additional information is available at www.asco.org/hematologic-malignancies-guidelines.

AB - PURPOSE To provide evidence-based recommendations on the treatment of multiple myeloma to practicing physicians and others. METHODS ASCO and Cancer Care Ontario convened an Expert Panel of medical oncology, surgery, radiation oncology, and advocacy experts to conduct a literature search, which included systematic reviews,meta-analyses, randomized controlled trials, and some phase II studies published from 2005 through 2018. Outcomes of interest included survival, progression-free survival, response rate, and quality of life. Expert Panel members used available evidence and informal consensus to develop evidence-based guideline recommendations. RESULTS The literature search identified 124 relevant studies to inform the evidence base for this guideline. RECOMMENDATIONS Evidence-based recommendations were developed for patients with multiple myeloma who are transplantation eligible and those who are ineligible and for patients with relapsed or refractory disease. Additional information is available at www.asco.org/hematologic-malignancies-guidelines.

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M3 - Review article

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SN - 0732-183X

VL - 37

SP - 1228

EP - 1263

JO - Journal of Clinical Oncology

JF - Journal of Clinical Oncology

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Treatment of multiple myeloma: ASCO and CCO joint clinical practice guideline

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