Treatment of metastatic rectal squamous cell carcinoma in a pregnant patient

Nathan S. Kau; Jeannie C. Kelly; Hyun Kim; Radhika Smith; Tyler J. Fraum; Kathleen Byrnes; Nikolaos A. Trikalinos; Olivia Aranha; Kevin Z. Li; Shiyuan Anabeth Liu; Rama Suresh

doi:10.1136/bcr-2023-257984

Treatment of metastatic rectal squamous cell carcinoma in a pregnant patient

Nathan S. Kau, Jeannie C. Kelly, Hyun Kim, Radhika Smith, Tyler J. Fraum, Kathleen Byrnes, Nikolaos A. Trikalinos, Olivia Aranha, Kevin Z. Li, Shiyuan Anabeth Liu, Rama Suresh

Research output: Contribution to journal › Article › peer-review

Abstract

Rectal squamous cell carcinoma is an exceedingly rare form of rectal cancer, with limited data available regarding its presentation and effective treatment. Rectal cancer occurring during pregnancy is uncommon as well. This is a case of metastatic rectal squamous cell carcinoma presenting in a 22-week pregnant, female patient in her early 30s. The patient was treated with 5-fluorouracil and cisplatin and delivered a healthy male child born via uncomplicated vaginal delivery at 35 weeks. This article demonstrates that despite the rare nature of this cancer, in the already rare context of pregnancy, effective and safe treatment is possible with a multidisciplinary team.

Original language	English
Article number	e257984
Journal	BMJ Case Reports
Volume	17
Issue number	2
DOIs	https://doi.org/10.1136/bcr-2023-257984
State	Published - Feb 20 2024

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title = "Treatment of metastatic rectal squamous cell carcinoma in a pregnant patient",

abstract = "Rectal squamous cell carcinoma is an exceedingly rare form of rectal cancer, with limited data available regarding its presentation and effective treatment. Rectal cancer occurring during pregnancy is uncommon as well. This is a case of metastatic rectal squamous cell carcinoma presenting in a 22-week pregnant, female patient in her early 30s. The patient was treated with 5-fluorouracil and cisplatin and delivered a healthy male child born via uncomplicated vaginal delivery at 35 weeks. This article demonstrates that despite the rare nature of this cancer, in the already rare context of pregnancy, effective and safe treatment is possible with a multidisciplinary team.",

author = "Kau, {Nathan S.} and Kelly, {Jeannie C.} and Hyun Kim and Radhika Smith and Fraum, {Tyler J.} and Kathleen Byrnes and Trikalinos, {Nikolaos A.} and Olivia Aranha and Li, {Kevin Z.} and Liu, {Shiyuan Anabeth} and Rama Suresh",

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doi = "10.1136/bcr-2023-257984",

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T1 - Treatment of metastatic rectal squamous cell carcinoma in a pregnant patient

AU - Kau, Nathan S.

AU - Kelly, Jeannie C.

AU - Kim, Hyun

AU - Smith, Radhika

AU - Fraum, Tyler J.

AU - Byrnes, Kathleen

AU - Trikalinos, Nikolaos A.

AU - Aranha, Olivia

AU - Li, Kevin Z.

AU - Liu, Shiyuan Anabeth

AU - Suresh, Rama

PY - 2024/2/20

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N2 - Rectal squamous cell carcinoma is an exceedingly rare form of rectal cancer, with limited data available regarding its presentation and effective treatment. Rectal cancer occurring during pregnancy is uncommon as well. This is a case of metastatic rectal squamous cell carcinoma presenting in a 22-week pregnant, female patient in her early 30s. The patient was treated with 5-fluorouracil and cisplatin and delivered a healthy male child born via uncomplicated vaginal delivery at 35 weeks. This article demonstrates that despite the rare nature of this cancer, in the already rare context of pregnancy, effective and safe treatment is possible with a multidisciplinary team.

AB - Rectal squamous cell carcinoma is an exceedingly rare form of rectal cancer, with limited data available regarding its presentation and effective treatment. Rectal cancer occurring during pregnancy is uncommon as well. This is a case of metastatic rectal squamous cell carcinoma presenting in a 22-week pregnant, female patient in her early 30s. The patient was treated with 5-fluorouracil and cisplatin and delivered a healthy male child born via uncomplicated vaginal delivery at 35 weeks. This article demonstrates that despite the rare nature of this cancer, in the already rare context of pregnancy, effective and safe treatment is possible with a multidisciplinary team.

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Treatment of metastatic rectal squamous cell carcinoma in a pregnant patient

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