TY - JOUR
T1 - Treatment of lymphangioleiomyomatosis
AU - Goodenberger, Daniel M.
AU - Dhand, Sandeep
AU - Eliasson, Arn H.
AU - Phillips, Yancy Y.
AU - Tenholder, Michael F.
AU - Goodwin, Thomas Murphy
AU - Zahner, Johannes
AU - Borst, Mathias M.
AU - Worth, Heinrich
AU - Raffin, Thomas A.
AU - Taylor, James R.
AU - Ryu, Jay
AU - Colby, Thomas V.
PY - 1991/7/4
Y1 - 1991/7/4
N2 - To the Editor: The article on lymphangioleiomyomatosis (LAM) by Taylor et al. (Nov. 1 issue)* was a very useful addition to the limited literature on the disease. I take issue with one of their recommendations, however. Despite their own finding that oophorectomy is not associated with an observable clinical benefit, they continue to recommend it as second-line therapy because studies to date cannot exclude a possible benefit. Perhaps the following hypothetical encounter with a patient will illustrate my point. “Mr. Jones, your open-lung biopsy showed a form of interstitial lung disease about which we know very little. The natural history.
AB - To the Editor: The article on lymphangioleiomyomatosis (LAM) by Taylor et al. (Nov. 1 issue)* was a very useful addition to the limited literature on the disease. I take issue with one of their recommendations, however. Despite their own finding that oophorectomy is not associated with an observable clinical benefit, they continue to recommend it as second-line therapy because studies to date cannot exclude a possible benefit. Perhaps the following hypothetical encounter with a patient will illustrate my point. “Mr. Jones, your open-lung biopsy showed a form of interstitial lung disease about which we know very little. The natural history.
UR - http://www.scopus.com/inward/record.url?scp=0025875452&partnerID=8YFLogxK
U2 - 10.1056/NEJM199107043250115
DO - 10.1056/NEJM199107043250115
M3 - Letter
C2 - 2046715
AN - SCOPUS:0025875452
SN - 0028-4793
VL - 325
SP - 63
EP - 64
JO - New England Journal of Medicine
JF - New England Journal of Medicine
IS - 1
ER -