Treatment of intractable constipation with orlistat: A report of three cases

Anthony H. Guarino

doi:10.1111/j.1526-4637.2005.00053.x

Treatment of intractable constipation with orlistat: A report of three cases

Anthony H. Guarino

Department of Anesthesiology

Research output: Contribution to journal › Article › peer-review

13 Scopus citations

Abstract

Intractable constipation is a frequent side effect of opioid treatment of chronic pain. Orlistat, an FDA approved pill for weight loss, has gastrointestinal side effects including fecal incontinence, oily spotting, fecal urgency, and increased defecation. The author postulated that capitalizing on the known side effects of orlistat and prescribing orlistat to obese, chronic pain patients with opioid induced constipation would provide relief. The following report describes three positive cases of the use of orlistat for the treatment of opioid related constipation.

Original language	English
Pages (from-to)	327-328
Number of pages	2
Journal	Pain Medicine
Volume	6
Issue number	4
DOIs	https://doi.org/10.1111/j.1526-4637.2005.00053.x
State	Published - Jul 2005

Keywords

Chronic Pain
Constipation
Opioids

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10.1111/j.1526-4637.2005.00053.x

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abstract = "Intractable constipation is a frequent side effect of opioid treatment of chronic pain. Orlistat, an FDA approved pill for weight loss, has gastrointestinal side effects including fecal incontinence, oily spotting, fecal urgency, and increased defecation. The author postulated that capitalizing on the known side effects of orlistat and prescribing orlistat to obese, chronic pain patients with opioid induced constipation would provide relief. The following report describes three positive cases of the use of orlistat for the treatment of opioid related constipation.",

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AB - Intractable constipation is a frequent side effect of opioid treatment of chronic pain. Orlistat, an FDA approved pill for weight loss, has gastrointestinal side effects including fecal incontinence, oily spotting, fecal urgency, and increased defecation. The author postulated that capitalizing on the known side effects of orlistat and prescribing orlistat to obese, chronic pain patients with opioid induced constipation would provide relief. The following report describes three positive cases of the use of orlistat for the treatment of opioid related constipation.

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KW - Constipation

KW - Opioids

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Treatment of intractable constipation with orlistat: A report of three cases

Abstract

Keywords

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