Treatment of intractable constipation with orlistat: A report of three cases

Anthony H. Guarino

Research output: Contribution to journalArticlepeer-review

8 Scopus citations

Abstract

Intractable constipation is a frequent side effect of opioid treatment of chronic pain. Orlistat, an FDA approved pill for weight loss, has gastrointestinal side effects including fecal incontinence, oily spotting, fecal urgency, and increased defecation. The author postulated that capitalizing on the known side effects of orlistat and prescribing orlistat to obese, chronic pain patients with opioid induced constipation would provide relief. The following report describes three positive cases of the use of orlistat for the treatment of opioid related constipation.

Original languageEnglish
Pages (from-to)327-328
Number of pages2
JournalPain Medicine
Volume6
Issue number4
DOIs
StatePublished - Jul 1 2005

Keywords

  • Chronic Pain
  • Constipation
  • Opioids

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