TY - JOUR
T1 - Treatment of intractable constipation with orlistat
T2 - A report of three cases
AU - Guarino, Anthony H.
PY - 2005/7/1
Y1 - 2005/7/1
N2 - Intractable constipation is a frequent side effect of opioid treatment of chronic pain. Orlistat, an FDA approved pill for weight loss, has gastrointestinal side effects including fecal incontinence, oily spotting, fecal urgency, and increased defecation. The author postulated that capitalizing on the known side effects of orlistat and prescribing orlistat to obese, chronic pain patients with opioid induced constipation would provide relief. The following report describes three positive cases of the use of orlistat for the treatment of opioid related constipation.
AB - Intractable constipation is a frequent side effect of opioid treatment of chronic pain. Orlistat, an FDA approved pill for weight loss, has gastrointestinal side effects including fecal incontinence, oily spotting, fecal urgency, and increased defecation. The author postulated that capitalizing on the known side effects of orlistat and prescribing orlistat to obese, chronic pain patients with opioid induced constipation would provide relief. The following report describes three positive cases of the use of orlistat for the treatment of opioid related constipation.
KW - Chronic Pain
KW - Constipation
KW - Opioids
UR - http://www.scopus.com/inward/record.url?scp=28444485353&partnerID=8YFLogxK
U2 - 10.1111/j.1526-4637.2005.00053.x
DO - 10.1111/j.1526-4637.2005.00053.x
M3 - Article
C2 - 16083464
AN - SCOPUS:28444485353
VL - 6
SP - 327
EP - 328
JO - Pain Medicine (United States)
JF - Pain Medicine (United States)
SN - 1526-2375
IS - 4
ER -