Treatment of dementia with lewy bodies

Brendon P. Boot, Eric M. McDade, Scott M. McGinnis, Bradley F. Boeve

Research output: Contribution to journalArticle

14 Scopus citations


Dementia with Lewy bodies (DLB) is a multisystem disorder with diverse disease expression. A treatment regime restricted to the cognitive aspects of the disease does no favor to patients. Instead, patients should be educated to recognize the symptoms of this multisystem involvement. There are no treatments that slow the progression of disease, but symptomatic treatments can be effective. When thinking about treatment, we find it useful to divide the symptoms and signs into five categories: (a) cognitive features, (b) neuropsychiatric features, (c) motor dysfunction, (d) autonomic dysfunction, and (e) sleep dysfunction. Clinicians, funding bodies and industry are increasingly recognizing the importance of this common and debilitating disease.

Original languageEnglish
Pages (from-to)738-764
Number of pages27
JournalCurrent Treatment Options in Neurology
Issue number6
StatePublished - Nov 13 2013
Externally publishedYes


  • Antipsychotic
  • Cholinesterase inhibitors
  • Dementia with Lewy bodies
  • Dysautonomia
  • Parkinson's disease dementia
  • REM sleep behavior disorder
  • Treatment

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