Treating diabetes by blocking a vascular growth factor

Peter Carmeliet; Brian W. Wong; Katrien De Bock

doi:10.1016/j.cmet.2012.10.015

Treating diabetes by blocking a vascular growth factor

Peter Carmeliet
, Brian W. Wong
, Katrien De Bock

Research output: Contribution to journal › Short survey › peer-review

12 Scopus citations

Abstract

Ectopic lipid deposition in muscle and liver is associated with the pathogenesis of type II diabetes. Hagberg et al. (2012) report that targeting the vascular endothelial growth factor (VEGF)-B restores insulin sensitivity and glucose tolerance by inhibiting endothelial-to-tissue lipid transport, opening promising avenues for diabetes therapy.

Original language	English
Pages (from-to)	553-555
Number of pages	3
Journal	Cell metabolism
Volume	16
Issue number	5
DOIs	https://doi.org/10.1016/j.cmet.2012.10.015
State	Published - Nov 7 2012

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10.1016/j.cmet.2012.10.015

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title = "Treating diabetes by blocking a vascular growth factor",

abstract = "Ectopic lipid deposition in muscle and liver is associated with the pathogenesis of type II diabetes. Hagberg et al. (2012) report that targeting the vascular endothelial growth factor (VEGF)-B restores insulin sensitivity and glucose tolerance by inhibiting endothelial-to-tissue lipid transport, opening promising avenues for diabetes therapy.",

author = "Peter Carmeliet and Wong, \{Brian W.\} and \{De Bock\}, Katrien",

year = "2012",

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T1 - Treating diabetes by blocking a vascular growth factor

AU - Carmeliet, Peter

AU - Wong, Brian W.

AU - De Bock, Katrien

PY - 2012/11/7

Y1 - 2012/11/7

N2 - Ectopic lipid deposition in muscle and liver is associated with the pathogenesis of type II diabetes. Hagberg et al. (2012) report that targeting the vascular endothelial growth factor (VEGF)-B restores insulin sensitivity and glucose tolerance by inhibiting endothelial-to-tissue lipid transport, opening promising avenues for diabetes therapy.

AB - Ectopic lipid deposition in muscle and liver is associated with the pathogenesis of type II diabetes. Hagberg et al. (2012) report that targeting the vascular endothelial growth factor (VEGF)-B restores insulin sensitivity and glucose tolerance by inhibiting endothelial-to-tissue lipid transport, opening promising avenues for diabetes therapy.

UR - https://www.scopus.com/pages/publications/84871402833

U2 - 10.1016/j.cmet.2012.10.015

DO - 10.1016/j.cmet.2012.10.015

M3 - Short survey

C2 - 23140637

AN - SCOPUS:84871402833

SN - 1550-4131

VL - 16

SP - 553

EP - 555

JO - Cell metabolism

JF - Cell metabolism

IS - 5

ER -

Treating diabetes by blocking a vascular growth factor

Abstract

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