Abstract
Thirty-one primary human renal carcinomas were transplanted into athymic mice of which ten produced tumors in the mouse host. Only tumors with a nuclear grade of 3 or 4 were successfully transplanted. The nuclear grades of the human tumor and transplant were similar; however, the cellular histology often varied. Patient prognosis appeared to be inversely related to successful tumor transplantation. In the transplant group, the 1-year survival was 30% in contrast to a 1-year survival of 83% among patients with renal cancers of similar stage and grade which did not produce tumors in the mice.
Original language | English |
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Pages (from-to) | 2650-2653 |
Number of pages | 4 |
Journal | Cancer research |
Volume | 45 |
Issue number | 6 |
State | Published - Jun 1 1985 |