TY - JOUR
T1 - ‘Transparent mice’
T2 - deep-tissue live imaging using food dyes
AU - Wang, Fei
AU - Zhou, Chao
N1 - Publisher Copyright:
© The Author(s) 2024.
PY - 2024/12
Y1 - 2024/12
N2 - Light scattering, resulting from refractive index mismatch, is the primary factor limiting imaging depth in biological tissue. In a study recently published in Science1, Ou et al. took an unconventional approach and employed highly absorbing molecules, such as food dye tartrazine, to increase the refractive index of water in the near-infrared wavelength range, which rendered tissue transparent in live mice.
AB - Light scattering, resulting from refractive index mismatch, is the primary factor limiting imaging depth in biological tissue. In a study recently published in Science1, Ou et al. took an unconventional approach and employed highly absorbing molecules, such as food dye tartrazine, to increase the refractive index of water in the near-infrared wavelength range, which rendered tissue transparent in live mice.
UR - http://www.scopus.com/inward/record.url?scp=85206123522&partnerID=8YFLogxK
U2 - 10.1038/s42003-024-07012-9
DO - 10.1038/s42003-024-07012-9
M3 - Comment/debate
C2 - 39394420
AN - SCOPUS:85206123522
SN - 2399-3642
VL - 7
JO - Communications Biology
JF - Communications Biology
IS - 1
M1 - 1307
ER -