Transmission of metabolic dysfunction across generations

Kathleen Jaeger, Jessica L. Saben, Kelle H. Moley

Research output: Contribution to journalReview articlepeer-review

21 Scopus citations


Recent human and animal studies investigating the roles of the genome, epigenome, and environmental cues have identified associations between offspring predisposition to life-long obesity/metabolic disease and epigenetic modifications such as DNA methylation. This review explores the mechanisms by which maternal exposures impair the health of not only the next generation but also potentially future generations of offspring.

Original languageEnglish
Pages (from-to)51-59
Number of pages9
Issue number1
StatePublished - Jan 2017


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