TY - JOUR
T1 - Tracking plasticity of individual human brains
AU - Newbold, Dillan J.
AU - Dosenbach, Nico UF
N1 - Publisher Copyright:
© 2021
PY - 2021/8
Y1 - 2021/8
N2 - Understanding how behavior affects human brain organization was the original motivation behind Precision Functional Mapping (PFM), a deep phenotyping approach to human neuroimaging. Here we review the original PFM studies, as well as research investigating the impact of sensory and/or motor deprivation, or disuse, on brain function. Next, we discuss precision functional mapping of brain plasticity, focusing on experiments that tracked casting of the dominant upper extremity with daily resting-state functional MRI scans. Mechanisms that shape brain circuits during early development may persist into adulthood, helping to maintain the organization of disused circuits.
AB - Understanding how behavior affects human brain organization was the original motivation behind Precision Functional Mapping (PFM), a deep phenotyping approach to human neuroimaging. Here we review the original PFM studies, as well as research investigating the impact of sensory and/or motor deprivation, or disuse, on brain function. Next, we discuss precision functional mapping of brain plasticity, focusing on experiments that tracked casting of the dominant upper extremity with daily resting-state functional MRI scans. Mechanisms that shape brain circuits during early development may persist into adulthood, helping to maintain the organization of disused circuits.
UR - http://www.scopus.com/inward/record.url?scp=85107089869&partnerID=8YFLogxK
U2 - 10.1016/j.cobeha.2021.04.018
DO - 10.1016/j.cobeha.2021.04.018
M3 - Review article
AN - SCOPUS:85107089869
SN - 2352-1546
VL - 40
SP - 161
EP - 168
JO - Current Opinion in Behavioral Sciences
JF - Current Opinion in Behavioral Sciences
ER -