Poor recovery of peripheral neuron damage caused by trauma is currently among the most common causes for low quality of life among US population. Disabilities caused by neuron damage and poor recovery tend to cause early workforce retirement, creating a gap in skilled workforce in the US. Recent studies suggest that biomechanical vectors play an important role in nerve recovery and functionality restoration. This preliminary study focuses on investigating of correlation between biomechanical properties of murine sciatic nerve and Brillouin elasticity data. Combined Brillouin-Raman spectroscopy was used as a label-free method of elasticity measurement.

Original languageEnglish
Title of host publicationOptical Biopsy XXI
Subtitle of host publicationToward Real-Time Spectroscopic Imaging and Diagnosis
EditorsRobert R. Alfano, Angela B. Seddon
ISBN (Electronic)9781510658516
StatePublished - 2023
EventOptical Biopsy XXI: Toward Real-Time Spectroscopic Imaging and Diagnosis 2023 - San Francisco, United States
Duration: Jan 31 2023Feb 1 2023

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
ISSN (Print)1605-7422


ConferenceOptical Biopsy XXI: Toward Real-Time Spectroscopic Imaging and Diagnosis 2023
Country/TerritoryUnited States
CitySan Francisco


  • Brillouin
  • Confocal microscopy
  • Drosophila
  • Elastic properties
  • Multimodal imaging
  • Photodynamic therapy
  • Raman
  • Scattering
  • Spectroscopy
  • Tissue elasticity
  • in vivo Imaging


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