TY - JOUR
T1 - Topographic organization in the brain
T2 - Searching for general principles
AU - Patel, Gaurav H.
AU - Kaplan, David M.
AU - Snyder, Lawrence H.
N1 - Funding Information:
The authors thank Sabine Kastner and Michael Arcaro for sharing data and discussing the various studies and Matthew Glasser for preparing Figure I D in Box 1 . They also thank their funding sources: G.H.P. – the Leon Levy Foundation, the American Psychiatric Foundation, and the National Institute of Mental Health (NIMH) (MH086466-04 and MH018870-25); and L.H.S. and D.M.K. – the National Eye Institute (EY012135) and the NIMH (MH102471).
PY - 2014/7
Y1 - 2014/7
N2 - The neurons comprising many cortical areas have long been known to be arranged topographically such that nearby neurons have receptive fields at nearby locations in the world. Although this type of organization may be universal in primary sensory and motor cortex, in this review we demonstrate that associative cortical areas may not represent the external world in a complete and continuous fashion. After reviewing evidence for novel principles of topographic organization in macaque lateral intraparietal area (LIP) - one of the most-studied associative areas in the parietal cortex - we explore the implications of these new principles for brain function.
AB - The neurons comprising many cortical areas have long been known to be arranged topographically such that nearby neurons have receptive fields at nearby locations in the world. Although this type of organization may be universal in primary sensory and motor cortex, in this review we demonstrate that associative cortical areas may not represent the external world in a complete and continuous fashion. After reviewing evidence for novel principles of topographic organization in macaque lateral intraparietal area (LIP) - one of the most-studied associative areas in the parietal cortex - we explore the implications of these new principles for brain function.
UR - http://www.scopus.com/inward/record.url?scp=84903155756&partnerID=8YFLogxK
U2 - 10.1016/j.tics.2014.03.008
DO - 10.1016/j.tics.2014.03.008
M3 - Review article
C2 - 24862252
AN - SCOPUS:84903155756
SN - 1364-6613
VL - 18
SP - 351
EP - 363
JO - Trends in Cognitive Sciences
JF - Trends in Cognitive Sciences
IS - 7
ER -