TY - JOUR
T1 - Tools for the Diagnosis and Management of Crohn's Disease
AU - Gergely, Maté
AU - Deepak, Parakkal
N1 - Funding Information:
M. Gergely has nothing to disclose. P. Deepak has served as a consultant or on an advisory board for Janssen, Pfizer, Prometheus Biosciences, Boehringer Ingelheim, AbbVie, Arena Pharmaceuticals, and Scipher Medicine Corporation; he has also received funding under a sponsored research agreement unrelated to the data in the paper from Takeda Pharmaceutical, Arena Pharmaceuticals, Bristol-Myers Squibb, and Boehringer Ingelheim.
PY - 2022/6
Y1 - 2022/6
N2 - Numerous tools have emerged over recent decades to aid in the increasingly complex management of patients with Crohn's disease (CD) beyond endoscopy, including video capsule endoscopy, magnetic resonance enterography, computed tomography enterography, a variety of biomarkers, and even wearable biosensors and smartphone applications. These tools have allowed for a more sophisticated and less invasive complementary approach to the evaluation of disease activity and treatment response in patients with CD. This article details the characteristics, practical application, and limitations of these various modalities and discusses how updated guidelines are now incorporating many of them into a treat-to-target strategy.
AB - Numerous tools have emerged over recent decades to aid in the increasingly complex management of patients with Crohn's disease (CD) beyond endoscopy, including video capsule endoscopy, magnetic resonance enterography, computed tomography enterography, a variety of biomarkers, and even wearable biosensors and smartphone applications. These tools have allowed for a more sophisticated and less invasive complementary approach to the evaluation of disease activity and treatment response in patients with CD. This article details the characteristics, practical application, and limitations of these various modalities and discusses how updated guidelines are now incorporating many of them into a treat-to-target strategy.
KW - Biomarker
KW - Endoscopy
KW - Enterography
KW - Small bowel Crohn's disease
KW - Treat-to-target
UR - http://www.scopus.com/inward/record.url?scp=85130861824&partnerID=8YFLogxK
U2 - 10.1016/j.gtc.2021.12.003
DO - 10.1016/j.gtc.2021.12.003
M3 - Review article
C2 - 35595412
AN - SCOPUS:85130861824
SN - 0889-8553
VL - 51
SP - 213
EP - 239
JO - Gastroenterology Clinics of North America
JF - Gastroenterology Clinics of North America
IS - 2
ER -