To skip or not to skip: choosing repriming to tolerate DNA damage

Annabel Quinet, Stephanie Tirman, Emily Cybulla, Alice Meroni, Alessandro Vindigni

Research output: Contribution to journalReview articlepeer-review

9 Scopus citations

Abstract

Replication stress response pathways allow DNA replication to tolerate obstacles with minimal delay in fork elongation. In this review, Quinet et al. discuss the molecular contexts in which cells choose repriming over template switching and translesion synthesis to tolerate these obstacles and the consequences of this choice on genome integrity.

Original languageEnglish
Pages (from-to)649-658
Number of pages10
JournalMolecular cell
Volume81
Issue number4
DOIs
StatePublished - Feb 18 2021

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