Josh Finnell, Jay F. Piccirillo, Carol Bauer, Thomas J. Brozoski, Alison Perring

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review


A computerized PubMed search of MEDLINE 1966-October 2005 was performed. The terms tinnitus and antidepressant-agents were exploded and the resulting articles were cross-referenced, yielding 26 articles. An additional search of the following subject headings was performed: tinnitus was cross-referenced with the textwords and medical subject headings antidepressive agents, antidepressive, antidepressant, amitriptyline, clomipramine, cyclobenzaprine, desipramine, desmethyldoxepin, dothiepin, doxepin, imipramine, iprindole, lofepramine, metapramine, mirtazapine, nortriptyline, opipramol, protriptyline, tianeptine, trimipramine. These resulting articles were then reviewed to identify those that met the following inclusion criteria: 1) patients with subjective tinnitus of ≥6-month duration between the ages of 18 and 70, 2) treatment with antidepressant agents versus placebo, 3) outcomes measured in terms of validated scales, and 4) randomized controlled trials.

Original languageEnglish
Title of host publicationEvidence-Based Otolaryngology
PublisherSpringer New York
Number of pages18
ISBN (Print)9780387244471
StatePublished - Dec 1 2008


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