Timolol plus maximum tolerated antiglaucoma therapy: A one-year followup study

Frank S. Ashburn, James E. Gillespie, Michael A. Kass, Bernard Becker

Research output: Contribution to journalArticlepeer-review

25 Scopus citations


Thirty-three eyes of 22 patients with primary open-angle glaucoma or severe ocular hypertension had topical timolol maleate added to their maximally tolerated medical regimens. With minimal side effects, 25 eyes (76%) could be treated medically for one year, and only eight eyes (24%) required filtering surgery. Thirteen (39%) of the medically treated eyes achieved intraocular pressures of 21 mm Hg or less. After the addition of timolol, 17 of the 33 eyes (52%) completed the one-year protocol with final mean intraocular pressure decreases of 5 mm Hg or more on medical therapy.

Original languageEnglish
Pages (from-to)389-394
Number of pages6
JournalSurvey of ophthalmology
Issue number6
StatePublished - 1979


  • filtering surgery
  • glaucoma
  • intraocular pressure
  • ocular hypertension
  • timolol maleate


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