Time to detoxify medical literature from guideline overdose

Dinesh Vyas, Arpita K. Vyas

Research output: Contribution to journalArticlepeer-review

3 Scopus citations


The current financial turmoil in the United States has been attributed to multiple reasons including healthcare expenditure. Health care spending has increased from 5.7 percent of the gross domestic product (GDP) in 1965 to 16 percent of the GDP in 2004. Healthcare is driven with a goal to provide best possible care available at that period of time. Guidelines are generally assumed to have the high level of certainty and security as conclusions generated by the conventional scientific method leading many clinicians to use guidelines as the final arbiters of care. To provide the standard of care, physicians follow guidelines, proposed by either groups of physicians or various medical societies or government organizations like National Comprehensive Cancer Network. This has lead to multiple tests for the patient and has not survived the test of time. This independence leads to lacunae in the standardization of guidelines, hence fooding of literature with multiple guidelines and confusion to patients and physicians and eventually overtreatment, ineffciency, and patient inconvenience. There is an urgent need to restrict articles with Guidelines and develop some strategy like have an intermediate stage of pre-guidelines and after 5-10 years of trials, a systematic launch of the Guidelines. There can be better ways than this for putting together guidelines as has been suggested by multiple authors and researchers.

Original languageEnglish
Pages (from-to)3331-3335
Number of pages5
JournalWorld Journal of Gastroenterology
Issue number26
StatePublished - 2012


  • Conflict of interest
  • Guidelines controversies in medicine
  • Health economics
  • Standard of care


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