Through-skull vasculature assessment using fluorescence brain imaging on murine models at around 800 nm

Hanh N.D. Le; Yung Tian A. Gau; Arman Rahmim; Dean F. Wong; Dwight E. Bergles; Jin U. Kang

doi:10.1117/12.2250240

Through-skull vasculature assessment using fluorescence brain imaging on murine models at around 800 nm

Hanh N.D. Le
, Yung Tian A. Gau
, Arman Rahmim
, Dean F. Wong
, Dwight E. Bergles
, Jin U. Kang

Precision Radiotheranostics Translation Center (PRTC)

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

1 Scopus citations

Abstract

We describe a scanning near-infrared fluorescence imager for through-skull non-invasive brain imaging on live murine models. The captured photoluminescence feature through scattering media was enhanced using a high sensitivity scientific CMOS sensor with the obtained spatial resolution of 15.63 μm, depth of field of 5 mm and an average local signal-to-noise ratio of 37.5 dB.

Original language	English
Title of host publication	Neural Imaging and Sensing
Editors	Jun Ding, Qingming Luo
Publisher	SPIE
ISBN (Electronic)	9781510605435
DOIs	https://doi.org/10.1117/12.2250240
State	Published - 2017
Event	Neural Imaging and Sensing - San Francisco, United States Duration: Jan 30 2017 → Jan 31 2017

Publication series

Name	Progress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume	10051
ISSN (Print)	1605-7422

Conference

Conference	Neural Imaging and Sensing
Country/Territory	United States
City	San Francisco
Period	01/30/17 → 01/31/17

Keywords

Brain imaging
Fluorescence imaging
Vasculature monitoring

Access to Document

10.1117/12.2250240

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Le, H. N. D., Gau, Y. T. A., Rahmim, A., Wong, D. F., Bergles, D. E., & Kang, J. U. (2017). Through-skull vasculature assessment using fluorescence brain imaging on murine models at around 800 nm. In J. Ding, & Q. Luo (Eds.), Neural Imaging and Sensing Article 100510M (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 10051). SPIE. https://doi.org/10.1117/12.2250240

@inproceedings{8ad2438555fc4c349bad3eed0246db7e,

title = "Through-skull vasculature assessment using fluorescence brain imaging on murine models at around 800 nm",

abstract = "We describe a scanning near-infrared fluorescence imager for through-skull non-invasive brain imaging on live murine models. The captured photoluminescence feature through scattering media was enhanced using a high sensitivity scientific CMOS sensor with the obtained spatial resolution of 15.63 μm, depth of field of 5 mm and an average local signal-to-noise ratio of 37.5 dB.",

keywords = "Brain imaging, Fluorescence imaging, Vasculature monitoring",

author = "Le, \{Hanh N.D.\} and Gau, \{Yung Tian A.\} and Arman Rahmim and Wong, \{Dean F.\} and Bergles, \{Dwight E.\} and Kang, \{Jin U.\}",

note = "Publisher Copyright: {\textcopyright} 2017 SPIE.; Neural Imaging and Sensing ; Conference date: 30-01-2017 Through 31-01-2017",

year = "2017",

doi = "10.1117/12.2250240",

language = "English",

series = "Progress in Biomedical Optics and Imaging - Proceedings of SPIE",

publisher = "SPIE",

editor = "Jun Ding and Qingming Luo",

booktitle = "Neural Imaging and Sensing",

}

Le, HND, Gau, YTA, Rahmim, A, Wong, DF, Bergles, DE & Kang, JU 2017, Through-skull vasculature assessment using fluorescence brain imaging on murine models at around 800 nm. in J Ding & Q Luo (eds), Neural Imaging and Sensing., 100510M, Progress in Biomedical Optics and Imaging - Proceedings of SPIE, vol. 10051, SPIE, Neural Imaging and Sensing, San Francisco, United States, 01/30/17. https://doi.org/10.1117/12.2250240

Through-skull vasculature assessment using fluorescence brain imaging on murine models at around 800 nm. / Le, Hanh N.D.; Gau, Yung Tian A.; Rahmim, Arman et al.
Neural Imaging and Sensing. ed. / Jun Ding; Qingming Luo. SPIE, 2017. 100510M (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 10051).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

TY - GEN

T1 - Through-skull vasculature assessment using fluorescence brain imaging on murine models at around 800 nm

AU - Le, Hanh N.D.

AU - Gau, Yung Tian A.

AU - Rahmim, Arman

AU - Wong, Dean F.

AU - Bergles, Dwight E.

AU - Kang, Jin U.

PY - 2017

Y1 - 2017

N2 - We describe a scanning near-infrared fluorescence imager for through-skull non-invasive brain imaging on live murine models. The captured photoluminescence feature through scattering media was enhanced using a high sensitivity scientific CMOS sensor with the obtained spatial resolution of 15.63 μm, depth of field of 5 mm and an average local signal-to-noise ratio of 37.5 dB.

AB - We describe a scanning near-infrared fluorescence imager for through-skull non-invasive brain imaging on live murine models. The captured photoluminescence feature through scattering media was enhanced using a high sensitivity scientific CMOS sensor with the obtained spatial resolution of 15.63 μm, depth of field of 5 mm and an average local signal-to-noise ratio of 37.5 dB.

KW - Brain imaging

KW - Fluorescence imaging

KW - Vasculature monitoring

UR - https://www.scopus.com/pages/publications/85019270449

U2 - 10.1117/12.2250240

DO - 10.1117/12.2250240

M3 - Conference contribution

AN - SCOPUS:85019270449

T3 - Progress in Biomedical Optics and Imaging - Proceedings of SPIE

BT - Neural Imaging and Sensing

A2 - Ding, Jun

A2 - Luo, Qingming

PB - SPIE

T2 - Neural Imaging and Sensing

Y2 - 30 January 2017 through 31 January 2017

ER -

Through-skull vasculature assessment using fluorescence brain imaging on murine models at around 800 nm

Abstract

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Conference

Keywords

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