Thromboembolism Prophylaxis in Hip Arthroplasty: Routine and High Risk Patients

Denis Nam, Ryan M. Nunley, Staci R. Johnson, James A. Keeney, John C. Clohisy, Robert L. Barrack

Research output: Contribution to journalArticle

20 Scopus citations


This study's purpose was to present the use of a risk stratification protocol in which "routine" risk patients receive a mobile compression device with aspirin and "high" risk patients receive warfarin for thromboprophylaxis after hip arthroplasty. 1859 hip arthroplasty patients were prospectively enrolled (1402 routine risk - 75.4%, 457 high risk - 24.6%). The cumulative rate of venous thromboembolism events was 0.5% in the routine versus 0.5% in the high-risk cohort within 6 weeks postoperatively (P=1.00). Patients in the routine risk cohort had a lower rate of major bleeding (0.5% versus 2.0%, P=0.006) and wound complications (0.2% versus 1.2%, P=0.01). Use of our risk stratification protocol allowed the avoidance of more aggressive anticoagulation in 75% of patients while achieving a low overall incidence of symptomatic VTE.

Original languageEnglish
Pages (from-to)2299-2303
Number of pages5
JournalJournal of Arthroplasty
Issue number12
StatePublished - Dec 1 2015


  • Bleeding
  • Deep venous thrombosis
  • Hip arthroplasty
  • Pulmonary embolism
  • Thromboprophylaxis

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