Three-Dimensional Gadolinium-Enhanced Coronary Magnetic Resonance Angiography: Initial Experience

Jie Zheng, Debiao Li, Kyongtae T. Bae, Pamela Woodard, E. Mark Haacke

Research output: Contribution to journalArticlepeer-review

38 Scopus citations


We present our initial experience on first-pass gadolinium-enhanced coronary artery magnetic resonance angiography (MRA). Three-dimensional segmented gradient-echo sequences were developed to image coronary arteries within a single breathhold during the injection of a double-dose contrast agent. Comparisons were made between a short TR of 2.7-msec (n = 5) and a long TR of 5.0-msec (n = 3) sequences in tenus of the signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR). An in-plane resolution of roughly 1 × 1 mm2 was achieved. Dramatic vascular signal enhancement by a factor of 3-5 was obtained in volunteers following the contrast agent injection, allowing for clear visualization of proximal coronary arteries. The longer TR scans generally performed better in terms of SNR and CNR improvement (approximately 50%) but allowed for less coverage. These preliminary results suggest that gadolinium-enhanced MRA is a useful tool to study proximal coronary arteries with breathhold, but for a larger coverage, a multiple dose approach may be necessary.

Original languageEnglish
Pages (from-to)33-41
Number of pages9
JournalJournal of Cardiovascular Magnetic Resonance
Issue number1
StatePublished - 1999


  • Contrast agents
  • Coronary artery
  • MR angiography


Dive into the research topics of 'Three-Dimensional Gadolinium-Enhanced Coronary Magnetic Resonance Angiography: Initial Experience'. Together they form a unique fingerprint.

Cite this