|Number of pages||7|
|Journal||International journal of radiation oncology, biology, physics|
|State||Published - Dec 1 1995|
- Pediatric neoplasms
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Three dimensional conformal radiation therapy in pediatric parameningeal rhabdomyosarcomas. / Michalski, Jeff M.; Sur, Ranjan K.; Harms, William B.; Purdy, James A.In: International journal of radiation oncology, biology, physics, Vol. 33, No. 5, 01.12.1995, p. 985-991.
Research output: Contribution to journal › Article › peer-review
TY - JOUR
T1 - Three dimensional conformal radiation therapy in pediatric parameningeal rhabdomyosarcomas
AU - Michalski, Jeff M.
AU - Sur, Ranjan K.
AU - Harms, William B.
AU - Purdy, James A.
N1 - Funding Information: Radiation therapy is a key element in the multimodality management of pediatric rhabdomyosarcoma (11). These tumors have the propensity to infiltrate beyond their organ of origin and invade adjacent normal tissues. To ensure adequate coverage of the infiltrating tumor edge, a margin of 2 to 5 cm around the prechemotherapy gross tumor is typically encompassedb y radiation therapy portals (17). Because of the risk of serious late morbidity related to the administration of irradiation in young patients, it may Reprint requestst o: Jeff M. Michalski, M.D., Mallinckrodt Institute of Radiology, Radiation Oncology Center, Box 8224, 4939 Children’s Place, Suite 5500, St. Louis, MO 63110. Acknowledgements-Dr. Sur’s participation in this study has been made possibleb y funding from the International Union Against Cancer( UICC), Geneva, through its InternationalC an- be tempting to reduce this margin in an effort to minimize radiation dose to surrounding critical structures (8). Inadequate margins have resulted in an increased rate of local failure and death, as demonstrated by the Intergroup Rhabdomyosarcoma Study in the management of para-meningeal tumors (16). The use of computed tomography (CT) for planning the shape of radiation fields directed to the primary tumor has made a significant impact in the local control of these tumors (5).
PY - 1995/12/1
Y1 - 1995/12/1
KW - Conformal
KW - Pediatric neoplasms
KW - Radiotherapy
UR - http://www.scopus.com/inward/record.url?scp=0028892226&partnerID=8YFLogxK
U2 - 10.1016/0360-3016(95)00551-X
DO - 10.1016/0360-3016(95)00551-X
M3 - Article
C2 - 7493860
AN - SCOPUS:0028892226
VL - 33
SP - 985
EP - 991
JO - International Journal of Radiation Oncology Biology Physics
JF - International Journal of Radiation Oncology Biology Physics
SN - 0360-3016
IS - 5