Thermoresponsive release of viable microfiltrated Circulating Tumor Cells (CTCs) for precision medicine applications

Zheng Ao; Erika Parasido; Siddarth Rawal; Anthony Williams; Richard Schlegel; Stephen Liu; Chris Albanese; Richard J. Cote; Ashutosh Agarwal; Ram H. Datar

doi:10.1039/c5lc01024a

Thermoresponsive release of viable microfiltrated Circulating Tumor Cells (CTCs) for precision medicine applications

Zheng Ao
, Erika Parasido
, Siddarth Rawal
, Anthony Williams
, Richard Schlegel
, Stephen Liu
, Chris Albanese
, Richard J. Cote
, Ashutosh Agarwal
, Ram H. Datar

Research output: Contribution to journal › Article › peer-review

24 Scopus citations

Abstract

Stimulus responsive release of Circulating Tumor Cells (CTCs), with high recovery rates from their capture platform, is highly desirable for off-chip analyses. Here, we present a temperature responsive polymer coating method to achieve both release as well as culture of viable CTCs captured from patient blood samples.

Original language	English
Pages (from-to)	4277-4282
Number of pages	6
Journal	Lab on a Chip
Volume	15
Issue number	22
DOIs	https://doi.org/10.1039/c5lc01024a
State	Published - 2015

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10.1039/c5lc01024a

Cite this

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title = "Thermoresponsive release of viable microfiltrated Circulating Tumor Cells (CTCs) for precision medicine applications",

abstract = "Stimulus responsive release of Circulating Tumor Cells (CTCs), with high recovery rates from their capture platform, is highly desirable for off-chip analyses. Here, we present a temperature responsive polymer coating method to achieve both release as well as culture of viable CTCs captured from patient blood samples.",

author = "Zheng Ao and Erika Parasido and Siddarth Rawal and Anthony Williams and Richard Schlegel and Stephen Liu and Chris Albanese and Cote, \{Richard J.\} and Ashutosh Agarwal and Datar, \{Ram H.\}",

note = "Publisher Copyright: {\textcopyright} 2015 The Royal Society of Chemistry.",

year = "2015",

doi = "10.1039/c5lc01024a",

language = "English",

volume = "15",

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T1 - Thermoresponsive release of viable microfiltrated Circulating Tumor Cells (CTCs) for precision medicine applications

AU - Ao, Zheng

AU - Parasido, Erika

AU - Rawal, Siddarth

AU - Williams, Anthony

AU - Schlegel, Richard

AU - Liu, Stephen

AU - Albanese, Chris

AU - Cote, Richard J.

AU - Agarwal, Ashutosh

AU - Datar, Ram H.

PY - 2015

Y1 - 2015

N2 - Stimulus responsive release of Circulating Tumor Cells (CTCs), with high recovery rates from their capture platform, is highly desirable for off-chip analyses. Here, we present a temperature responsive polymer coating method to achieve both release as well as culture of viable CTCs captured from patient blood samples.

AB - Stimulus responsive release of Circulating Tumor Cells (CTCs), with high recovery rates from their capture platform, is highly desirable for off-chip analyses. Here, we present a temperature responsive polymer coating method to achieve both release as well as culture of viable CTCs captured from patient blood samples.

UR - https://www.scopus.com/pages/publications/84946019627

U2 - 10.1039/c5lc01024a

DO - 10.1039/c5lc01024a

M3 - Article

C2 - 26426331

AN - SCOPUS:84946019627

SN - 1473-0197

VL - 15

SP - 4277

EP - 4282

JO - Lab on a Chip

JF - Lab on a Chip

IS - 22

ER -

Thermoresponsive release of viable microfiltrated Circulating Tumor Cells (CTCs) for precision medicine applications

Abstract

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