Thermodynamic fluctuations in a reacting system measurement by fluorescence correlation spectroscopy

Douglas Magde; Elliot Elson; W. W. Webb

doi:10.1103/PhysRevLett.29.705

Thermodynamic fluctuations in a reacting system measurement by fluorescence correlation spectroscopy

Douglas Magde, Elliot Elson, W. W. Webb

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Abstract

The temporal correlations of thermodynamic concentration fluctuations have been measured in a chemically reactive system at equilibrium by observing fluctuations of the fluorescence of a reaction product. The experiment yields the chemical rate constants and diffusion coefficients and shows the coupling among them. Data are reported for binding of ethidium bromide to DNA.

Original language	English
Pages (from-to)	705-708
Number of pages	4
Journal	Physical Review Letters
Volume	29
Issue number	11
DOIs	https://doi.org/10.1103/PhysRevLett.29.705
State	Published - 1972

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abstract = "The temporal correlations of thermodynamic concentration fluctuations have been measured in a chemically reactive system at equilibrium by observing fluctuations of the fluorescence of a reaction product. The experiment yields the chemical rate constants and diffusion coefficients and shows the coupling among them. Data are reported for binding of ethidium bromide to DNA.",

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AU - Elson, Elliot

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Thermodynamic fluctuations in a reacting system measurement by fluorescence correlation spectroscopy

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