Therapies for Hemorrhagic Transformation in Acute Ischemic Stroke

Joshua A. Stone, Joshua Z. Willey, Salah Keyrouz, James Butera, Ryan A. McTaggart, Shawna Cutting, Brian Silver, Bradford Thompson, Karen L. Furie, Shadi Yaghi

Research output: Contribution to journalReview article

10 Scopus citations

Abstract

Hemorrhagic transformation occurs in about 10–15% of patients with acute ischemic stroke. The treatment of hemorrhagic conversion is complex and includes blood pressure management, reversing coagulopathy, and managing its complications including increased intracranial pressure. Future research should be directed on identifying indications to treat and use of appropriate homeostatic regimens to effectively reverse the different anticoagulants and thrombolytic agents in an attempt to improve outcomes of patients with hemorrhagic transformation.

Original languageEnglish
Article number1
JournalCurrent Treatment Options in Neurology
Volume19
Issue number1
DOIs
StatePublished - Jan 1 2017

Keywords

  • Anticoagulation
  • Hemorrhagic transformation
  • Ischemic stroke
  • Thrombolytic therapy
  • Treatment

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    Stone, J. A., Willey, J. Z., Keyrouz, S., Butera, J., McTaggart, R. A., Cutting, S., Silver, B., Thompson, B., Furie, K. L., & Yaghi, S. (2017). Therapies for Hemorrhagic Transformation in Acute Ischemic Stroke. Current Treatment Options in Neurology, 19(1), [1]. https://doi.org/10.1007/s11940-017-0438-5