Therapeutic levels of functional human factor X in rats after retroviral-mediated hepatic gene therapy

Keyphrases

• Retroviral Vector 100%
• Therapeutic Levels 100%
• Hepatic Gene Therapy 100%
• Human Factors 100%
• Hepatocytes 66%
• Antitrypsin 66%
• Long-lived 33%
• Specific Antibodies 33%
• Direct Expression 33%
• Complementary DNA (cDNA) 33%
• Hemostasis 33%
• Liver Regeneration 33%
• Co-immunoprecipitation (co-IP) 33%
• Expression Level 33%
• Hemophilia 33%
• Bleeding Disorders 33%
• Human-specific 33%
• Rat Hepatocytes 33%
• Liver-specific Promoter 33%
• X Gene 33%
• Serious Bleeding 33%
• Chromogenic Substrate Assay 33%
• Human Gene Therapy 33%
• Factor X Deficiency 33%

Biochemistry, Genetics and Molecular Biology

• Gene Therapy 100%
• Factor X 100%
• Retrovirus Vector 50%
• Hepatocyte 50%
• Promoter Region 33%
• Liver Regeneration 16%
• Immunoprecipitation 16%
• Hemostasis 16%
• Haemophilia A 16%

Pharmacology, Toxicology and Pharmaceutical Science

• Blood Clotting Factor 10 100%
• Retrovirus Vector 60%
• Trypsin Inhibitor 40%
• Complementary DNA 20%
• Immunoprecipitation 20%
• Bleeding Disorder 20%
• Blood Stasis 20%
• Haemophilia A 20%
• Chromogenic Substrate 20%
• Blood Clotting Factor 10 Deficiency 20%