TY - JOUR
T1 - Theoretical Models of Neural Development
AU - Goodhill, Geoffrey J.
N1 - Funding Information:
I thank Brendan Bicknell, Pranesh Padmanabhan, and Marcus Triplett Jan Mölter for helpful feedback on an earlier version. I gratefully acknowledge funding from the Australian National Health and Medical Research Council (Project Grant 1107986)and the Australian Research Council (Grant DP170102263).
Funding Information:
I thank Brendan Bicknell, Pranesh Padmanabhan, and Marcus Triplett Jan Mölter for helpful feedback on an earlier version. I gratefully acknowledge funding from the Australian National Health and Medical Research Council (Project Grant 1107986 ) and the Australian Research Council (Grant DP170102263 ).
Publisher Copyright:
© 2018 The Author(s)
PY - 2018/10/26
Y1 - 2018/10/26
N2 - Constructing a functioning nervous system requires the precise orchestration of a vast array of mechanical, molecular, and neural-activity-dependent cues. Theoretical models can play a vital role in helping to frame quantitative issues, reveal mathematical commonalities between apparently diverse systems, identify what is and what is not possible in principle, and test the abilities of specific mechanisms to explain the data. This review focuses on the progress that has been made over the last decade in our theoretical understanding of neural development.
AB - Constructing a functioning nervous system requires the precise orchestration of a vast array of mechanical, molecular, and neural-activity-dependent cues. Theoretical models can play a vital role in helping to frame quantitative issues, reveal mathematical commonalities between apparently diverse systems, identify what is and what is not possible in principle, and test the abilities of specific mechanisms to explain the data. This review focuses on the progress that has been made over the last decade in our theoretical understanding of neural development.
KW - Biological Sciences
KW - Developmental Neuroscience
KW - In Silico Biology
KW - Neuroscience
KW - Theoretical Neuroscience
UR - http://www.scopus.com/inward/record.url?scp=85065559678&partnerID=8YFLogxK
U2 - 10.1016/j.isci.2018.09.017
DO - 10.1016/j.isci.2018.09.017
M3 - Review article
AN - SCOPUS:85065559678
VL - 8
SP - 183
EP - 199
JO - iScience
JF - iScience
SN - 2589-0042
ER -