TY - JOUR
T1 - Theoretical models of diffusion-attenuated magnetic resonance signal in biological tissues
AU - Sukstanskii, Alexander L.
AU - Yablonskiy, Dmitriy A.
N1 - Funding Information:
This work was supported by US NIH Grant No. R01AG054513.
Publisher Copyright:
© 2020 Author(s).
PY - 2020/8/1
Y1 - 2020/8/1
N2 - Diffusion Magnetic Resonance Imaging (MRI) plays a very important role in studying biological tissue cellular structure and functioning both in health and disease. Proper interpretation of experimental data requires the development of theoretical models that connect the diffusion MRI signal to salient features of tissue microstructure at the cellular level. In this short review, we present some theoretical approaches to describing diffusion-attenuated magnetic resonance signals. These range from the models based on statistical properties of water molecules diffusing in the tissue- cellular environment, to models allowing exact analytical calculation of the magnetic resonance signal in a specific single-compartment environment. Such theoretical analysis gives important insights into mechanisms contributing to the formation of diffusion magnetic resonance signal and its connection to biological tissue cellular structure.
AB - Diffusion Magnetic Resonance Imaging (MRI) plays a very important role in studying biological tissue cellular structure and functioning both in health and disease. Proper interpretation of experimental data requires the development of theoretical models that connect the diffusion MRI signal to salient features of tissue microstructure at the cellular level. In this short review, we present some theoretical approaches to describing diffusion-attenuated magnetic resonance signals. These range from the models based on statistical properties of water molecules diffusing in the tissue- cellular environment, to models allowing exact analytical calculation of the magnetic resonance signal in a specific single-compartment environment. Such theoretical analysis gives important insights into mechanisms contributing to the formation of diffusion magnetic resonance signal and its connection to biological tissue cellular structure.
UR - http://www.scopus.com/inward/record.url?scp=85094957138&partnerID=8YFLogxK
U2 - 10.1063/10.0001538
DO - 10.1063/10.0001538
M3 - Article
AN - SCOPUS:85094957138
SN - 1063-777X
VL - 46
JO - Low Temperature Physics
JF - Low Temperature Physics
IS - 8
M1 - 768
ER -