The y chromosome as a regulatory element shaping immune cell transcriptomes and susceptibility to autoimmune disease

Keyphrases

• Autoimmune Disease 100%
• Regulatory Elements 100%
• Immune Cells 100%
• Transcriptome 100%
• Chromosome Y 100%
• Experimental Autoimmune Encephalomyelitis 30%
• CD4+ T Cells 20%
• Gene Regulation 20%
• Genome-wide Expression 20%
• Sexual Dimorphism 20%
• Regulatory Property 20%
• Regulatory Genomics 20%
• C57BL 10%
• Drosophilidae 10%
• Macrophages 10%
• Healthy Controls 10%
• CD4+ T 10%
• Copy number Variation 10%
• Multiple Sclerosis Treatment 10%
• Complex Disease 10%
• Evolutionarily Conserved 10%
• Mouse Strain 10%
• Copy number 10%
• Genetic Background 10%
• Genetic Elements 10%
• Gene Copy number 10%
• Therapeutic Management 10%
• Gene Regulatory Programs 10%
• Conserved Mechanisms 10%
• Multi-copy 10%
• Natural Variation 10%
• Myocarditis 10%
• Immune Parameters 10%
• DNA Elements 10%
• Inverse Correlation 10%
• Upregulated Genes 10%
• Consomic Mouse 10%
• Consomic Strain 10%
• SJL Mice 10%
• Y Polymorphism 10%
• Experimental Myocarditis 10%
• Mammalian Chromosome 10%

Immunology and Microbiology

• Immunocompetent Cell 100%
• Autoimmune Disease 100%
• Transcriptome 100%
• Y Chromosome 100%
• T-Helper Cell 30%
• Experimental Autoimmune Encephalomyelitis 30%
• Gene Expression 20%
• Gene Control 20%
• Sex Difference 20%
• Myocarditis 20%
• Macrophage 10%
• Regulator Gene 10%
• Mouse Strain 10%
• Multiple Sclerosis 10%
• Genetic Background 10%
• Autosome 10%
• Swiss James Lambert Mouse 10%
• Copy Number Variation 10%
• Chromosome Substitution Strain 10%

Biochemistry, Genetics and Molecular Biology

• Regulatory Element 100%
• Y Chromosome 100%
• Immunocompetent Cell 100%
• Transcriptome 100%
• T Cell 30%
• CD4 30%
• Gene Control 20%
• Gene Expression 20%
• Sex Difference 20%
• Genetics 10%
• Copy-Number Variation 10%
• Animal Model 10%
• Macrophage 10%
• Mouse Strain 10%
• Genetic Background 10%
• Locus Control Region 10%
• Autosome 10%
• Chromosome Substitution Strain 10%
• Swiss James Lambert Mouse 10%