The wrapping loop and Rap1 C-terminal (RCT) domain of yeast Rap1 modulate access to different DNA binding modes

Erik A. Feldmann, Paolo De Bona, Roberto Galletto

Research output: Contribution to journalArticle

7 Scopus citations

Abstract

Background: Rap1 is a general regulator of transcription and a component of the telomere. Results: Rap1 binds DNA in at least two binding modes. Conclusion: Access to binding modes in vitro is affected by different regions of the protein. Significance: The ability of Rap1 to access different binding modes may impact its functions.

Original languageEnglish
Pages (from-to)11455-11466
Number of pages12
JournalJournal of Biological Chemistry
Volume290
Issue number18
DOIs
StatePublished - May 1 2015

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