The value of long-term angiographic follow-up following Pipeline embolization of intracranial aneurysms

David C. Lauzier, Samuel J. Cler, Arindam R. Chatterjee, Joshua W. Osbun, Christopher J. Moran, Akash P. Kansagra

Research output: Contribution to journalArticlepeer-review

14 Scopus citations


Background Flow diversion of intracranial aneurysms with the Pipeline Embolization Device (PED) is commonly performed, but the value of long-term angiographic follow-up has not been rigorously evaluated. Here we examine the prevalence of actionable findings of aneurysm recurrence and development of in-stent stenosis in a cohort of patients that underwent long-term angiographic follow-up at multiple time points. Methods Angiographic data from eligible patients were retrospectively assessed for aneurysm occlusion, in-stent stenosis, and aneurysm regrowth or recurrence. Patients were included in this study if they underwent angiographic imaging at 6 months post-treatment and at least one later time point. Results 100% (132/132) of aneurysms occluded at 6 months remained occluded at final follow-up. 85.7% (6/7), 56.3% (27/48), and 25% (6/24) of aneurysms with entry remnant, subtotal filling, and total filling, respectively, at 6 months were completely occluded at final follow-up. 98.7% (147/149) of PED constructs that demonstrated no stenosis at 6 months demonstrated no stenosis at final angiography, while 44.4% (8/18) of PED constructs demonstrating in-stent stenosis at 6 months had resolution of stenosis on final angiography. Conclusions Among patients who undergo treatment of intracranial aneurysms with PED, the value of long-term angiography in patients demonstrating complete aneurysm occlusion and no in-stent stenosis on 6 month post-treatment angiography is low.

Original languageEnglish
Pages (from-to)585-588
Number of pages4
JournalJournal of NeuroInterventional Surgery
Issue number6
StatePublished - 2022


  • Aneurysm
  • Flow diverter


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