TY - JOUR
T1 - The use of warfarin for dvt prophylaxis following hip and knee arthroplasty
T2 - How often are patients within their target INR range?
AU - Nam, Denis
AU - Sadhu, Anita
AU - Hirsh, Jeffrey
AU - Keeney, James A.
AU - Nunley, Ryan M.
AU - Barrack, Robert L.
N1 - Publisher Copyright:
© 2014 Elsevier Inc.
PY - 2015/2/1
Y1 - 2015/2/1
N2 - The purpose of this study was to determine the percentage of time that patients are therapeutic when prescribed warfarin for chemical thromboprophylaxis following a hip or knee arthroplasty procedure. One hundred eighty-four patients receiving warfarin for 4. weeks postoperatively, dosed using a Web-application accounting for patient demographics, INR levels, and concomitant medication use, were included. Patients with a target INR range between 1.7 and 2.7 were therapeutic for only 54.4% of the time (32.5% subtherapeutic, 13.0% supratherapeutic) while patients with a target INR range between 2.0 and 3.0 were therapeutic for only 45.9% of the time (39.2% subtherapeutic, 14.8% supratherapeutic). Patients receiving warfarin for chemical thromboprophylaxis are within their targeted INR range for only a limited period of time during their postoperative course.
AB - The purpose of this study was to determine the percentage of time that patients are therapeutic when prescribed warfarin for chemical thromboprophylaxis following a hip or knee arthroplasty procedure. One hundred eighty-four patients receiving warfarin for 4. weeks postoperatively, dosed using a Web-application accounting for patient demographics, INR levels, and concomitant medication use, were included. Patients with a target INR range between 1.7 and 2.7 were therapeutic for only 54.4% of the time (32.5% subtherapeutic, 13.0% supratherapeutic) while patients with a target INR range between 2.0 and 3.0 were therapeutic for only 45.9% of the time (39.2% subtherapeutic, 14.8% supratherapeutic). Patients receiving warfarin for chemical thromboprophylaxis are within their targeted INR range for only a limited period of time during their postoperative course.
KW - Coumadin
KW - Thromboprophylaxis
KW - Total knee arthroplasty
KW - Venous thromboembolism
KW - Warfarin
UR - http://www.scopus.com/inward/record.url?scp=84925194367&partnerID=8YFLogxK
U2 - 10.1016/j.arth.2014.08.032
DO - 10.1016/j.arth.2014.08.032
M3 - Article
C2 - 25261182
AN - SCOPUS:84925194367
VL - 30
SP - 315
EP - 319
JO - Journal of Arthroplasty
JF - Journal of Arthroplasty
SN - 0883-5403
IS - 2
ER -