The use of nifedipine for the treatment of achalasia in children

Martin Maksimak, David H. Perlmutter, Harland S. Winter

Research output: Contribution to journalArticlepeer-review

60 Scopus citations

Abstract

Four adolescents with achalasia were treated with nifedipine. All the patients’ symptoms improved dramatically. On manometric evaluation, following oral nifedipine, the lower esophageal sphincter pressure decreased approximately 50%. No change in esophageal peristaltic activity was noted. Side effects were minimal; two patients had mild headache initially. Nifedipine, which is commonly used in adult patients with achalasia, may be beneficial for short-term symptomatic relief in children until more definitive therapy can be performed.

Original languageEnglish
Pages (from-to)883-886
Number of pages4
JournalJournal of pediatric gastroenterology and nutrition
Volume5
Issue number6
DOIs
StatePublished - Nov 1986

Keywords

  • Achalasia
  • Nifedipine

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