TY - JOUR
T1 - The Tumor Microbiome in Pancreatic Cancer
T2 - Bacteria and Beyond
AU - McAllister, Florencia
AU - Khan, Md Abdul Wadud
AU - Helmink, Beth
AU - Wargo, Jennifer A.
N1 - Funding Information:
F.M. is supported by the AGA, MD Anderson Philanthropic Funds and Stand Up To Cancer-Lustgarten Foundation Pancreatic Cancer Interception Translational Cancer ( SU2C-AACR-DT25-17 ) administered by the AACR . B.A.H. is supported by National Institutes of Health T32 CA 009599 and the MD Anderson Cancer Center support grant ( P30 CA016672 ).
Funding Information:
F.M. is supported by the AGA, MD Anderson Philanthropic Funds and Stand Up To Cancer-Lustgarten Foundation Pancreatic Cancer Interception Translational Cancer (SU2C-AACR-DT25-17) administered by the AACR. B.A.H. is supported by National Institutes of Health T32 CA 009599 and the MD Anderson Cancer Center support grant (P30 CA016672). J.A.W. is an inventor on a U.S. patent application (PCT/US17/53.717) submitted by the UT MDACC and reports compensation for speaker's bureau and honoraria from Imedex, Dava Oncology, Omniprex, Illumina, Gilead, MedImmune, and Bristol-Myers Squibb (BMS). J.A.W. serves as a consultant and advisory board member for Roche and Genentech, Novartis, AstraZeneca, GlaxoSmithKline (GSK), BMS, Merck, Biothera Pharmaceuticals, and Microbiome DX and receives research support from GSK, Roche/Genentech, BMS, and Novartis. F.M. is an inventor on a US patent application on tumor microbiome submitted by the UT MDACC.
Publisher Copyright:
© 2019
PY - 2019/12/9
Y1 - 2019/12/9
N2 - There is increasing appreciation of the microbial influence on cancer, with emerging evidence about the tumor microbiome and crosstalk with the gut microbiome. A great example of this is pancreatic cancer, in which intra-tumoral microbes such as bacteria and fungi have been shown to contribute to carcinogenesis and therapeutic responses, both positively and negatively.
AB - There is increasing appreciation of the microbial influence on cancer, with emerging evidence about the tumor microbiome and crosstalk with the gut microbiome. A great example of this is pancreatic cancer, in which intra-tumoral microbes such as bacteria and fungi have been shown to contribute to carcinogenesis and therapeutic responses, both positively and negatively.
UR - http://www.scopus.com/inward/record.url?scp=85075864241&partnerID=8YFLogxK
U2 - 10.1016/j.ccell.2019.11.004
DO - 10.1016/j.ccell.2019.11.004
M3 - Article
C2 - 31951558
AN - SCOPUS:85075864241
VL - 36
SP - 577
EP - 579
JO - Cancer Cell
JF - Cancer Cell
SN - 1535-6108
IS - 6
ER -